Effect of osmotic stress on the expression of TRPV4 and BKCa channels and possible interaction with ERK1/2 and p38 in cultured equine chondrocytes

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Effect of osmotic stress on the expression of TRPV4 and BKCa channels and possible interaction with ERK1/2 and p38 in cultured equine chondrocytes

The metabolic activity of articular chondrocytes is influenced by osmotic alterations that occur in articular cartilage secondary to mechanical load. The mechanisms that sense and transduce mechanical signals from cell swelling and initiate volume regulation are poorly understood. The purpose of thi...

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Bibliographic Details
Main Authors:	Hdud, Ismail M., Mobasheri, Ali, Loughna, Paul
Format:	Article
Language:	English
Published:	American Physiological Society 2014
Subjects:	cartilage; chondrocyte; mitogen-activated protein kinase; osmotic; transient receptor potential vanilloid 4
Online Access:	https://eprints.nottingham.ac.uk/46619/

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