Cell imaging by phonon microscopy: sub-optical wavelength ultrasound for non-invasive imaging

The mechanical properties of cells play an important role in cell function and behavior. This paper presents recent developments that have enabled the use of laser-generated phonons (ultrasound) with sub-optical wavelengths to look inside living cells. The phonons reveal contrast from changes in the...

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Bibliographic Details
Main Authors: Perez-Cota, Fernando, Smith, Richard J., Moradi, Emilia, Leija, Anaid Lugo, Velickovic, Ksenija, Marques, Leonel, Webb, Kevin F., Symonds, Michael E., Sottile, Virginie, Elsheikha, Hanny, Clark, Matt
Format: Article
Published: Wiley 2017
Online Access:https://eprints.nottingham.ac.uk/46556/
Description
Summary:The mechanical properties of cells play an important role in cell function and behavior. This paper presents recent developments that have enabled the use of laser-generated phonons (ultrasound) with sub-optical wavelengths to look inside living cells. The phonons reveal contrast from changes in the elasticity of the cell and can provide high resolution three dimensional images.