Designing clinical trials for assessing the effectiveness of interventions for tinnitus
In the face of finite resources, allocations of research and healthcare funding are dependent upon high-quality evidence. Historically, tinnitus has been the poor cousin of hearing science, with low-quality clinical research providing unreliable estimates of effect, and with devices marketed for tin...
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| Format: | Article |
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Sage
2017
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| Online Access: | https://eprints.nottingham.ac.uk/46495/ |
| _version_ | 1848797339892842496 |
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| author | Hall, Deborah A. |
| author_facet | Hall, Deborah A. |
| author_sort | Hall, Deborah A. |
| building | Nottingham Research Data Repository |
| collection | Online Access |
| description | In the face of finite resources, allocations of research and healthcare funding are dependent upon high-quality evidence. Historically, tinnitus has been the poor cousin of hearing science, with low-quality clinical research providing unreliable estimates of effect, and with devices marketed for tinnitus without strong evidence for those product claims. However, the tinnitus field is changing. Key opinion leaders have recently made calls to the field to improve the design, implementation and reporting of clinical trials, and there is growing intersectoral collaboration. The Tonndorf Lecture presented at the 1st World Tinnitus Congress and 12th International Tinnitus Seminar in Warsaw, Poland provided an opportunity to reflect on the present and future progress of tinnitus research and treatment and what is needed for the field to achieve success. The content of that lecture is summarised in this review article. The main debate concerns the selection and reporting of outcomes in clinical trials of tinnitus. Comprehensive reviews of the literature confirm the diversity of the personal impact of tinnitus, and illustrate a lack of consensus in what aspects of tinnitus should be assessed and reported in a clinical trial. An innovative project is described which engages the global tinnitus community (patients and professionals alike) in working together. This project seeks to improve future tinnitus research by creating an evidence-based consensus about minimum reporting standards for outcomes in clinical trials of a tinnitus intervention. The output will be a core set of important and critical outcomes to be measured and reported in all clinical trials. |
| first_indexed | 2025-11-14T20:02:19Z |
| format | Article |
| id | nottingham-46495 |
| institution | University of Nottingham Malaysia Campus |
| institution_category | Local University |
| last_indexed | 2025-11-14T20:02:19Z |
| publishDate | 2017 |
| publisher | Sage |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | nottingham-464952020-05-04T19:14:10Z https://eprints.nottingham.ac.uk/46495/ Designing clinical trials for assessing the effectiveness of interventions for tinnitus Hall, Deborah A. In the face of finite resources, allocations of research and healthcare funding are dependent upon high-quality evidence. Historically, tinnitus has been the poor cousin of hearing science, with low-quality clinical research providing unreliable estimates of effect, and with devices marketed for tinnitus without strong evidence for those product claims. However, the tinnitus field is changing. Key opinion leaders have recently made calls to the field to improve the design, implementation and reporting of clinical trials, and there is growing intersectoral collaboration. The Tonndorf Lecture presented at the 1st World Tinnitus Congress and 12th International Tinnitus Seminar in Warsaw, Poland provided an opportunity to reflect on the present and future progress of tinnitus research and treatment and what is needed for the field to achieve success. The content of that lecture is summarised in this review article. The main debate concerns the selection and reporting of outcomes in clinical trials of tinnitus. Comprehensive reviews of the literature confirm the diversity of the personal impact of tinnitus, and illustrate a lack of consensus in what aspects of tinnitus should be assessed and reported in a clinical trial. An innovative project is described which engages the global tinnitus community (patients and professionals alike) in working together. This project seeks to improve future tinnitus research by creating an evidence-based consensus about minimum reporting standards for outcomes in clinical trials of a tinnitus intervention. The output will be a core set of important and critical outcomes to be measured and reported in all clinical trials. Sage 2017-10-27 Article PeerReviewed Hall, Deborah A. (2017) Designing clinical trials for assessing the effectiveness of interventions for tinnitus. Trends In Hearing, 21 . pp. 1-12. ISSN 2331-2165 heterogeneity outcomes assessment clinical trial synthesis population characteristics http://journals.sagepub.com/doi/10.1177/2331216517736689 doi:10.1177/2331216517736689 doi:10.1177/2331216517736689 |
| spellingShingle | heterogeneity outcomes assessment clinical trial synthesis population characteristics Hall, Deborah A. Designing clinical trials for assessing the effectiveness of interventions for tinnitus |
| title | Designing clinical trials for assessing the effectiveness of interventions for tinnitus |
| title_full | Designing clinical trials for assessing the effectiveness of interventions for tinnitus |
| title_fullStr | Designing clinical trials for assessing the effectiveness of interventions for tinnitus |
| title_full_unstemmed | Designing clinical trials for assessing the effectiveness of interventions for tinnitus |
| title_short | Designing clinical trials for assessing the effectiveness of interventions for tinnitus |
| title_sort | designing clinical trials for assessing the effectiveness of interventions for tinnitus |
| topic | heterogeneity outcomes assessment clinical trial synthesis population characteristics |
| url | https://eprints.nottingham.ac.uk/46495/ https://eprints.nottingham.ac.uk/46495/ https://eprints.nottingham.ac.uk/46495/ |