Restoring mucosal barrier function and modifying macrophage phenotype with an extracellular matrix hydrogel: potential therapy for ulcerative colitis

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Restoring mucosal barrier function and modifying macrophage phenotype with an extracellular matrix hydrogel: potential therapy for ulcerative colitis

Background & Aims: Despite advances in therapeutic options, more than half of all patients with ulcerative colitis (UC) do not achieve long-term remission, many require colectomy, and the disease still has a marked negative impact on quality of life. Extracellular matrix (ECM) bioscaffolds facil...

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Bibliographic Details
Main Authors:	Keane, Timothy J., Dziki, Jenna, Sobieski, Eric, Smoulder, Adam, Castleton, Arthur A, Turner, Neill J., White, Lisa J., Badylak, Stephen F.
Format:	Article
Published:	Oxford Academic Press 2017
Subjects:	Extracellular matrix macrophage activation barrier function
Online Access:	https://eprints.nottingham.ac.uk/46418/

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