Mild synthesis of poly(HEMA)-networks as well-defined nanoparticles in supercritical carbon dioxide

Free-radical dispersion polymerisation of 2-hydroxyethyl methacrylate was carried out in supercritical carbon dioxide (scCO2) in the presence of stabilisers based on polyethylene oxide (PEO) and poly(heptadecafluorodecyl acrylate) (PFDA). Different architectures of copolymers (random, palm-tree and...

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Main Authors: Parilti, R., Alaimo, D., Grignard, B., Boury, F., Howdle, S.M., Jerome, C.
Format: Article
Published: Royal Society of Chemistry 2017
Online Access:https://eprints.nottingham.ac.uk/45570/
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author Parilti, R.
Alaimo, D.
Grignard, B.
Boury, F.
Howdle, S.M.
Jerome, C.
author_facet Parilti, R.
Alaimo, D.
Grignard, B.
Boury, F.
Howdle, S.M.
Jerome, C.
author_sort Parilti, R.
building Nottingham Research Data Repository
collection Online Access
description Free-radical dispersion polymerisation of 2-hydroxyethyl methacrylate was carried out in supercritical carbon dioxide (scCO2) in the presence of stabilisers based on polyethylene oxide (PEO) and poly(heptadecafluorodecyl acrylate) (PFDA). Different architectures of copolymers (random, palm-tree and diblock) were tested for their surface tension, cloud point and as a stabilising agent. The diblock architecture was found to be the best candidate resulting in poly(HEMA) spherical particles with a size of 316 nm. Furthermore, the effect of the CO2-phobic block (PEO) in the diblock architecture was investigated by using three different chain lengths (1000, 2000, 5000 g mol−1). By optimizing the stabiliser composition and structure, mild reaction conditions have been identified allowing us to obtain well-defined spherical cross-linked poly(HEMA) particles with a mean diameter of unprecedented low size (216 nm) at a temperature as low as 35 °C.
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spelling nottingham-455702020-05-04T18:51:53Z https://eprints.nottingham.ac.uk/45570/ Mild synthesis of poly(HEMA)-networks as well-defined nanoparticles in supercritical carbon dioxide Parilti, R. Alaimo, D. Grignard, B. Boury, F. Howdle, S.M. Jerome, C. Free-radical dispersion polymerisation of 2-hydroxyethyl methacrylate was carried out in supercritical carbon dioxide (scCO2) in the presence of stabilisers based on polyethylene oxide (PEO) and poly(heptadecafluorodecyl acrylate) (PFDA). Different architectures of copolymers (random, palm-tree and diblock) were tested for their surface tension, cloud point and as a stabilising agent. The diblock architecture was found to be the best candidate resulting in poly(HEMA) spherical particles with a size of 316 nm. Furthermore, the effect of the CO2-phobic block (PEO) in the diblock architecture was investigated by using three different chain lengths (1000, 2000, 5000 g mol−1). By optimizing the stabiliser composition and structure, mild reaction conditions have been identified allowing us to obtain well-defined spherical cross-linked poly(HEMA) particles with a mean diameter of unprecedented low size (216 nm) at a temperature as low as 35 °C. Royal Society of Chemistry 2017-06-26 Article PeerReviewed Parilti, R., Alaimo, D., Grignard, B., Boury, F., Howdle, S.M. and Jerome, C. (2017) Mild synthesis of poly(HEMA)-networks as well-defined nanoparticles in supercritical carbon dioxide. Journal of Materials Chemistry B, 5 . pp. 5806-5815. ISSN 2050-750X http://pubs.rsc.org/is/content/articlelanding/2017/tb/c7tb00740j#!divAbstract doi:10.1039/C7TB00740J doi:10.1039/C7TB00740J
spellingShingle Parilti, R.
Alaimo, D.
Grignard, B.
Boury, F.
Howdle, S.M.
Jerome, C.
Mild synthesis of poly(HEMA)-networks as well-defined nanoparticles in supercritical carbon dioxide
title Mild synthesis of poly(HEMA)-networks as well-defined nanoparticles in supercritical carbon dioxide
title_full Mild synthesis of poly(HEMA)-networks as well-defined nanoparticles in supercritical carbon dioxide
title_fullStr Mild synthesis of poly(HEMA)-networks as well-defined nanoparticles in supercritical carbon dioxide
title_full_unstemmed Mild synthesis of poly(HEMA)-networks as well-defined nanoparticles in supercritical carbon dioxide
title_short Mild synthesis of poly(HEMA)-networks as well-defined nanoparticles in supercritical carbon dioxide
title_sort mild synthesis of poly(hema)-networks as well-defined nanoparticles in supercritical carbon dioxide
url https://eprints.nottingham.ac.uk/45570/
https://eprints.nottingham.ac.uk/45570/
https://eprints.nottingham.ac.uk/45570/