Intrinsic disorder in the partitioning protein KorB persists after co-operative complex formation with operator DNA and KorA

Intrinsic disorder in the partitioning protein KorB persists after co-operative complex formation with operator DNA and KorA

The ParB protein, KorB, from the RK2 plasmid is required for DNA partitioning and transcriptional repression. It acts co-operatively with other proteins, including the repressor KorA. Like many multifunctional proteins, KorB contains regions of intrinsically disordered structure, existing in a large...

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Bibliographic Details
Main Authors: Hyde, Eva I., Callow, Phillip, Rajasekar, Karthik V., timmins, Peter, Patel, Trushar Patel, Siligardi, Giuliano, Hussain, Rohanah, White, Scott A., Thomas, Christopher M., Scott, David J.
Format: Article
Published: Portland Press 2017
Subjects:
circular dichroism; intrinsically disordered regions; small-angle neutron scattering experiments; small-angle X-ray scattering;
Online Access:https://eprints.nottingham.ac.uk/45548/

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