Evidence that Listeria innocua modulates its membrane’s stored curvature elastic stress, but not fluidity, through the cell cycle

This paper reports that the abundances of endogenous cardiolipin and phosphatidylethanolamine halve during elongation of the Gram-positive bacterium Listeria innocua. The lyotropic phase behaviour of model lipid systems that describe these modulations in lipid composition indicate that the average s...

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Main Authors: Furse, Samuel, Jakubec, Martin, Rise, Frode, Williams, Huw E.L., Rees, Catherine, Halskau, Øyvind
Format: Article
Published: Nature Publishing Group 2017
Online Access:https://eprints.nottingham.ac.uk/45345/
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author Furse, Samuel
Jakubec, Martin
Rise, Frode
Williams, Huw E.L.
Rees, Catherine
Halskau, Øyvind
author_facet Furse, Samuel
Jakubec, Martin
Rise, Frode
Williams, Huw E.L.
Rees, Catherine
Halskau, Øyvind
author_sort Furse, Samuel
building Nottingham Research Data Repository
collection Online Access
description This paper reports that the abundances of endogenous cardiolipin and phosphatidylethanolamine halve during elongation of the Gram-positive bacterium Listeria innocua. The lyotropic phase behaviour of model lipid systems that describe these modulations in lipid composition indicate that the average stored curvature elastic stress of the membrane is reduced on elongation of the cell, while the fluidity appears to be maintained. These findings suggest that phospholipid metabolism is linked to the cell cycle and that changes in membrane composition can lower the energetic barrier to the succeeding stage of the cell cycle. This therefore suggests a means by which bacteria can manage the physical properties of their membranes through the cell cycle.
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spelling nottingham-453452020-05-04T19:00:23Z https://eprints.nottingham.ac.uk/45345/ Evidence that Listeria innocua modulates its membrane’s stored curvature elastic stress, but not fluidity, through the cell cycle Furse, Samuel Jakubec, Martin Rise, Frode Williams, Huw E.L. Rees, Catherine Halskau, Øyvind This paper reports that the abundances of endogenous cardiolipin and phosphatidylethanolamine halve during elongation of the Gram-positive bacterium Listeria innocua. The lyotropic phase behaviour of model lipid systems that describe these modulations in lipid composition indicate that the average stored curvature elastic stress of the membrane is reduced on elongation of the cell, while the fluidity appears to be maintained. These findings suggest that phospholipid metabolism is linked to the cell cycle and that changes in membrane composition can lower the energetic barrier to the succeeding stage of the cell cycle. This therefore suggests a means by which bacteria can manage the physical properties of their membranes through the cell cycle. Nature Publishing Group 2017-08-14 Article PeerReviewed Furse, Samuel, Jakubec, Martin, Rise, Frode, Williams, Huw E.L., Rees, Catherine and Halskau, Øyvind (2017) Evidence that Listeria innocua modulates its membrane’s stored curvature elastic stress, but not fluidity, through the cell cycle. Scientific Reports, 7 . 8012/1-8012/11. ISSN 2045-2322 http://www.nature.com/articles/s41598-017-06855-z doi:10.1038/s41598-017-06855-z doi:10.1038/s41598-017-06855-z
spellingShingle Furse, Samuel
Jakubec, Martin
Rise, Frode
Williams, Huw E.L.
Rees, Catherine
Halskau, Øyvind
Evidence that Listeria innocua modulates its membrane’s stored curvature elastic stress, but not fluidity, through the cell cycle
title Evidence that Listeria innocua modulates its membrane’s stored curvature elastic stress, but not fluidity, through the cell cycle
title_full Evidence that Listeria innocua modulates its membrane’s stored curvature elastic stress, but not fluidity, through the cell cycle
title_fullStr Evidence that Listeria innocua modulates its membrane’s stored curvature elastic stress, but not fluidity, through the cell cycle
title_full_unstemmed Evidence that Listeria innocua modulates its membrane’s stored curvature elastic stress, but not fluidity, through the cell cycle
title_short Evidence that Listeria innocua modulates its membrane’s stored curvature elastic stress, but not fluidity, through the cell cycle
title_sort evidence that listeria innocua modulates its membrane’s stored curvature elastic stress, but not fluidity, through the cell cycle
url https://eprints.nottingham.ac.uk/45345/
https://eprints.nottingham.ac.uk/45345/
https://eprints.nottingham.ac.uk/45345/