The chronic stages of bovine Fasciola hepatica are dominated by CD4 T-Cell exhaustion

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The chronic stages of bovine Fasciola hepatica are dominated by CD4 T-Cell exhaustion

Fasciola hepatica infection of ruminants leads to non-resolving chronic infection, as patency develops, there is switching to a TGF-β and IL-10 led response. Here, we explore the responses of CD4 T-cells within the major draining lymph nodes. We found minimal expression of Foxp3 within CD4 cells but...

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Bibliographic Details
Main Authors:	Sachdev, Divya, Gough, Kevin C., Flynn, Robin J.
Format:	Article
Published:	Frontiers Media 2017
Online Access:	https://eprints.nottingham.ac.uk/45334/

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