Effect of delivery method on the efficacy of Salmonella vaccination in chickens
To investigate whether the efficacy of live vaccines is influenced by the mode of vaccine delivery, a widely-used UK live commercial Salmonella Enteritidis vaccine was delivered to pullet chicks either by spray, in drinking water, or in combination with a bivalent vaccine containing inactivated Salm...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Published: |
BMJ Publishing Group
2010
|
| Online Access: | https://eprints.nottingham.ac.uk/45240/ |
| _version_ | 1848797095281033216 |
|---|---|
| author | Atterbury, Robert J. Morris, V. Harrison, D. Tucker, V. Allen, V.M. Davies, R.H. Carrique-Mas, J.J. |
| author_facet | Atterbury, Robert J. Morris, V. Harrison, D. Tucker, V. Allen, V.M. Davies, R.H. Carrique-Mas, J.J. |
| author_sort | Atterbury, Robert J. |
| building | Nottingham Research Data Repository |
| collection | Online Access |
| description | To investigate whether the efficacy of live vaccines is influenced by the mode of vaccine delivery, a widely-used UK live commercial Salmonella Enteritidis vaccine was delivered to pullet chicks either by spray, in drinking water, or in combination with a bivalent vaccine containing inactivated Salmonella Enteritidis and Salmonella Typhimurium. The birds were subsequently challenged with 102 or 108 colony-forming units (cfu) of Salmonella Enteritidis through drinking water at either six or 20 weeks of age. Ten days after the challenge, the birds were euthanased and their caecal contents cultured for Salmonella. All of the vaccinated groups contained fewer Salmonella Enteritidis-positive birds than the unvaccinated groups. The ‘spray-vaccinated’ group contained significantly fewer Salmonella Enteritidis-positive birds than the ‘water-vaccinated’ group after challenge with 108 cfu at 20 weeks. However, there was little or no difference at the other challenge time points between the groups that received vaccine through different modes of delivery. |
| first_indexed | 2025-11-14T19:58:25Z |
| format | Article |
| id | nottingham-45240 |
| institution | University of Nottingham Malaysia Campus |
| institution_category | Local University |
| last_indexed | 2025-11-14T19:58:25Z |
| publishDate | 2010 |
| publisher | BMJ Publishing Group |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | nottingham-452402020-05-04T20:24:58Z https://eprints.nottingham.ac.uk/45240/ Effect of delivery method on the efficacy of Salmonella vaccination in chickens Atterbury, Robert J. Morris, V. Harrison, D. Tucker, V. Allen, V.M. Davies, R.H. Carrique-Mas, J.J. To investigate whether the efficacy of live vaccines is influenced by the mode of vaccine delivery, a widely-used UK live commercial Salmonella Enteritidis vaccine was delivered to pullet chicks either by spray, in drinking water, or in combination with a bivalent vaccine containing inactivated Salmonella Enteritidis and Salmonella Typhimurium. The birds were subsequently challenged with 102 or 108 colony-forming units (cfu) of Salmonella Enteritidis through drinking water at either six or 20 weeks of age. Ten days after the challenge, the birds were euthanased and their caecal contents cultured for Salmonella. All of the vaccinated groups contained fewer Salmonella Enteritidis-positive birds than the unvaccinated groups. The ‘spray-vaccinated’ group contained significantly fewer Salmonella Enteritidis-positive birds than the ‘water-vaccinated’ group after challenge with 108 cfu at 20 weeks. However, there was little or no difference at the other challenge time points between the groups that received vaccine through different modes of delivery. BMJ Publishing Group 2010-07 Article PeerReviewed Atterbury, Robert J., Morris, V., Harrison, D., Tucker, V., Allen, V.M., Davies, R.H. and Carrique-Mas, J.J. (2010) Effect of delivery method on the efficacy of Salmonella vaccination in chickens. Veterinary Record, 167 (5). pp. 161-164. ISSN 2042-7670 http://veterinaryrecord.bmj.com/content/167/5/161# doi:10.1136/vr.b4884 doi:10.1136/vr.b4884 |
| spellingShingle | Atterbury, Robert J. Morris, V. Harrison, D. Tucker, V. Allen, V.M. Davies, R.H. Carrique-Mas, J.J. Effect of delivery method on the efficacy of Salmonella vaccination in chickens |
| title | Effect of delivery method on the efficacy of Salmonella vaccination in chickens |
| title_full | Effect of delivery method on the efficacy of Salmonella vaccination in chickens |
| title_fullStr | Effect of delivery method on the efficacy of Salmonella vaccination in chickens |
| title_full_unstemmed | Effect of delivery method on the efficacy of Salmonella vaccination in chickens |
| title_short | Effect of delivery method on the efficacy of Salmonella vaccination in chickens |
| title_sort | effect of delivery method on the efficacy of salmonella vaccination in chickens |
| url | https://eprints.nottingham.ac.uk/45240/ https://eprints.nottingham.ac.uk/45240/ https://eprints.nottingham.ac.uk/45240/ |