Muscle thickness correlates to muscle cross sectional area in the assessment of strength training induced hypertrophy
Aim: Muscle thickness (MT) measured by ultrasound has been used to estimate cross-sectional area (measured by CT and MRI) at a single time-point. We tested whether MT could be used as a valid marker of MRI determined muscle anatomical cross-sectional area (ACSA) and volume changes following resistan...
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| Format: | Article |
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Wiley
2017
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| Online Access: | https://eprints.nottingham.ac.uk/45129/ |
| _version_ | 1848797075475529728 |
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| author | Franchi, Martino V. Longo, Stefano Mallinson, Joanne E. Quinlan, Jonathan I. Taylor, Tariq Greenhaff, Paul L. Narici, Marco V. |
| author_facet | Franchi, Martino V. Longo, Stefano Mallinson, Joanne E. Quinlan, Jonathan I. Taylor, Tariq Greenhaff, Paul L. Narici, Marco V. |
| author_sort | Franchi, Martino V. |
| building | Nottingham Research Data Repository |
| collection | Online Access |
| description | Aim: Muscle thickness (MT) measured by ultrasound has been used to estimate cross-sectional area (measured by CT and MRI) at a single time-point. We tested whether MT could be used as a valid marker of MRI determined muscle anatomical cross-sectional area (ACSA) and volume changes following resistance training (RT).
Methods: Nine healthy, young, male volunteers (24±2 y.o., BMI 24.1±2.8 kg/m2) had vastus lateralis (VL) muscle volume (VOL) and ACSA mid (at 50% of femur length, FL) assessed by MRI, and VL MT measured by ultrasound at 50% FL. Measurements were taken at baseline and after 12 weeks of isokinetic RT. Differences between baseline and post-training were assessed by Student’s paired t-test. The relationships between MRI and ultrasound measurements were tested by Pearson’s correlation.
Results: After RT, MT increased by 7.5±6.1% (p<0.001), ACSAmid by 5.2±5% (p<0.001) and VOL by 5.0±6.9% (p<0.05) (values: means±S.D.). Positive correlations were found, at baseline and 12 weeks, between MT and ACSAmid (r=0.82, p<0.001 and r=0.73, p<0.001, respectively), and between MT and VOL (r=0.76, p < 0.001 and r=0.73, p < 0.001, respectively). The % change in MT with training was correlated with % change in ACSAmid (r=0.69, p = 0.01), but not % change in VOL (r= 0.33, p>0.05).
Conclusions: These data support evidence that MT is a reliable index of muscle ACSAmid and VOL at a single time-point. MT changes following RT are associated with parallel changes in muscle ACSAmid but not with the changes in VOL, highlighting the impact of RT on regional hypertrophy. |
| first_indexed | 2025-11-14T19:58:07Z |
| format | Article |
| id | nottingham-45129 |
| institution | University of Nottingham Malaysia Campus |
| institution_category | Local University |
| last_indexed | 2025-11-14T19:58:07Z |
| publishDate | 2017 |
| publisher | Wiley |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | nottingham-451292024-08-15T15:24:10Z https://eprints.nottingham.ac.uk/45129/ Muscle thickness correlates to muscle cross sectional area in the assessment of strength training induced hypertrophy Franchi, Martino V. Longo, Stefano Mallinson, Joanne E. Quinlan, Jonathan I. Taylor, Tariq Greenhaff, Paul L. Narici, Marco V. Aim: Muscle thickness (MT) measured by ultrasound has been used to estimate cross-sectional area (measured by CT and MRI) at a single time-point. We tested whether MT could be used as a valid marker of MRI determined muscle anatomical cross-sectional area (ACSA) and volume changes following resistance training (RT). Methods: Nine healthy, young, male volunteers (24±2 y.o., BMI 24.1±2.8 kg/m2) had vastus lateralis (VL) muscle volume (VOL) and ACSA mid (at 50% of femur length, FL) assessed by MRI, and VL MT measured by ultrasound at 50% FL. Measurements were taken at baseline and after 12 weeks of isokinetic RT. Differences between baseline and post-training were assessed by Student’s paired t-test. The relationships between MRI and ultrasound measurements were tested by Pearson’s correlation. Results: After RT, MT increased by 7.5±6.1% (p<0.001), ACSAmid by 5.2±5% (p<0.001) and VOL by 5.0±6.9% (p<0.05) (values: means±S.D.). Positive correlations were found, at baseline and 12 weeks, between MT and ACSAmid (r=0.82, p<0.001 and r=0.73, p<0.001, respectively), and between MT and VOL (r=0.76, p < 0.001 and r=0.73, p < 0.001, respectively). The % change in MT with training was correlated with % change in ACSAmid (r=0.69, p = 0.01), but not % change in VOL (r= 0.33, p>0.05). Conclusions: These data support evidence that MT is a reliable index of muscle ACSAmid and VOL at a single time-point. MT changes following RT are associated with parallel changes in muscle ACSAmid but not with the changes in VOL, highlighting the impact of RT on regional hypertrophy. Wiley 2017-09-21 Article PeerReviewed Franchi, Martino V., Longo, Stefano, Mallinson, Joanne E., Quinlan, Jonathan I., Taylor, Tariq, Greenhaff, Paul L. and Narici, Marco V. (2017) Muscle thickness correlates to muscle cross sectional area in the assessment of strength training induced hypertrophy. Scandinavian Journal of Medicine & Science in Sports, 28 (3). pp. 846-853. ISSN 1600-0838 MRI ; ACSA ; Ultrasound; Volume http://onlinelibrary.wiley.com/doi/10.1111/sms.12961/abstract doi:10.1111/sms.12961 doi:10.1111/sms.12961 |
| spellingShingle | MRI ; ACSA ; Ultrasound; Volume Franchi, Martino V. Longo, Stefano Mallinson, Joanne E. Quinlan, Jonathan I. Taylor, Tariq Greenhaff, Paul L. Narici, Marco V. Muscle thickness correlates to muscle cross sectional area in the assessment of strength training induced hypertrophy |
| title | Muscle thickness correlates to muscle cross sectional area in the assessment of strength training induced hypertrophy |
| title_full | Muscle thickness correlates to muscle cross sectional area in the assessment of strength training induced hypertrophy |
| title_fullStr | Muscle thickness correlates to muscle cross sectional area in the assessment of strength training induced hypertrophy |
| title_full_unstemmed | Muscle thickness correlates to muscle cross sectional area in the assessment of strength training induced hypertrophy |
| title_short | Muscle thickness correlates to muscle cross sectional area in the assessment of strength training induced hypertrophy |
| title_sort | muscle thickness correlates to muscle cross sectional area in the assessment of strength training induced hypertrophy |
| topic | MRI ; ACSA ; Ultrasound; Volume |
| url | https://eprints.nottingham.ac.uk/45129/ https://eprints.nottingham.ac.uk/45129/ https://eprints.nottingham.ac.uk/45129/ |