CD95-mediated calcium signaling promotes T helper 17 trafficking to inflamed organs in lupus-prone mice

CD95-mediated calcium signaling promotes T helper 17 trafficking to inflamed organs in lupus-prone mice

CD95 ligand (CD95L) is expressed by immune cells and triggers apoptotic death. Metalloprotease-cleaved CD95L (cl-CD95L) is released into the bloodstream but does not trigger apoptotic signaling. Hence, the pathophysiological role of cl-CD95L remains unclear. We observed that skin-derived endothelial...

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Bibliographic Details
Main Authors: Poissonnier, Amanda, Sanséau, Doriane, Le Gallo, Matthieu, Malleter, Marine, Levoin, Nicolas, Viel, Roselyne, Morere, Lucie, Penna, Aubin, Blanco, Patrick, Dupuy, Alain, Poizeau, Florence, Fautrel, Alain, Seneschal, Julien, Jouan, Florence, Ritz, Jerome, Forcade, Edouard, Rioux, Nathalie, Contin-Bordes, Cécile, Ducret, Thomas, Vacher, Anne-Marie, Barrow, Paul A., Flynn, Robin J., Vacher, Pierre, Legembre, Patrick
Format: Article
Published: Elsevier 2016
Online Access:https://eprints.nottingham.ac.uk/45101/

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