Fish oil omega-3 fatty acids partially prevent lipid-induced insulin resistance in human skeletal muscle without limiting acylcarnitine accumulation
Acylcarnitine accumulation in skeletal muscle and plasma has been observed in numerous models of mitochondrial lipid overload and insulin resistance. Fish oil n3PUFA (omega-3 polyunsaturated fatty acids) are thought to protect against lipid-induced insulin resistance. The present study tested the hy...
| Main Authors: | Stephens, Francis B., Mendis, Buddhike, Shannon, Chris E., Cooper, Scott, Ortori, Catharine A., Barrett, David A., Mansell, Peter, Tsintzas, Kostas |
|---|---|
| Format: | Article |
| Published: |
Portland Press
2014
|
| Subjects: | |
| Online Access: | https://eprints.nottingham.ac.uk/44965/ |
Similar Items
Increasing cardiac pyruvate dehydrogenase flux during chronic hypoxia improves acute hypoxic tolerance
by: Handzlik, Michal, et al.
Published: (2018)
by: Handzlik, Michal, et al.
Published: (2018)
Insulin resistance in health and disease: exploring the role of disuse skeletal muscle atrophy, testosterone and Beta-Hydroxy-Beta-Methylbutyrate (HMB) in young and older men
by: Shanthaveerappa Rudrappa, Supreeth
Published: (2021)
by: Shanthaveerappa Rudrappa, Supreeth
Published: (2021)
Exploring the effects of ageing, cancer, and exercise on skeletal muscle mitochondrial function
by: Smart, Thomas
Published: (2024)
by: Smart, Thomas
Published: (2024)
Development of a liquid chromatography-mass spectrometry method to investigate branched chain amino acid and acylcarnitine metabolism in type 2 diabetes
by: Pabla, Pardeep
Published: (2021)
by: Pabla, Pardeep
Published: (2021)
Large-scale synthesis of both symmetrical and unsymmetrical triacylglycerols containing docosahexaenoic acid
by: Andrews, P., et al.
Published: (2008)
by: Andrews, P., et al.
Published: (2008)
The effect of dietary omega-3 and -6 polyunsaturated fatty acids on ovine ovarian function and the pre-implantation embryo
by: Hughes, Jaime
Published: (2011)
by: Hughes, Jaime
Published: (2011)
Omega-3 Index, fish consumption, use of fish oil supplements and first clinical diagnosis of central nervous system demyelination
by: Daly, Alison, et al.
Published: (2021)
by: Daly, Alison, et al.
Published: (2021)
Antioxidant and omega-3 fatty acid intake in the modulation of respiratory illness & asthma in children
by: Nikravan, Ramin
Published: (2011)
by: Nikravan, Ramin
Published: (2011)
Effect of dietary omega-3 fatty acid supplementation on frailty related phenotypes in older adults: a systematic review and meta-analysis protocol
by: Stocks, Joanne, et al.
Published: (2018)
by: Stocks, Joanne, et al.
Published: (2018)
Omega-3 fatty acids. What consumers need to know
by: McManus, Alexandra, et al.
Published: (2010)
by: McManus, Alexandra, et al.
Published: (2010)
Subcritical water extraction of lipid containing omega-3 from microalgae Nannochloropsis gaditana
by: Ho, Bernard Chon Han
Published: (2020)
by: Ho, Bernard Chon Han
Published: (2020)
Mitochondria and diabetes: An intriguing pathogenetic role
by: Newsholme, Philip, et al.
Published: (2012)
by: Newsholme, Philip, et al.
Published: (2012)
Obesity mediated dysregulation in the expression and action of myostatin
by: Wilhelmsen, Andrew
Published: (2022)
by: Wilhelmsen, Andrew
Published: (2022)
Comparative heterogeneity, molecular weights and viscosities of xanthans of different pyruvate and acetate content
by: Erten, Tayyibe, et al.
Published: (2014)
by: Erten, Tayyibe, et al.
Published: (2014)
Mitochondrial haemoglobin and ATP synthase – molecular interactions in health and disease
by: Ebanks, Brad
Published: (2023)
by: Ebanks, Brad
Published: (2023)
The role of bioactive lipids and lipid binding proteins in skeletal muscle
by: Mohd Noor, Mohd Fadly
Published: (2019)
by: Mohd Noor, Mohd Fadly
Published: (2019)
The heterogeneity of the functional, metabolic, and molecular responses of skeletal muscle and clinical adaptations to exercise training in pre-clinical and human models
by: Farrash, Wesam
Published: (2020)
by: Farrash, Wesam
Published: (2020)
Recent advances in Omega-3: Health benefits, sources, products and bioavailability
by: Nichols, P., et al.
Published: (2014)
by: Nichols, P., et al.
Published: (2014)
Mouse mitochondrial lipid composition is defined by age in brain and muscle
by: Pollard, Amelia K., et al.
Published: (2017)
by: Pollard, Amelia K., et al.
Published: (2017)
Seafood and omega-3s for maternal and child mental health
by: Newton, Wendy, et al.
Published: (2013)
by: Newton, Wendy, et al.
Published: (2013)
Functional characterization of alcohol dehydrogenase genes in Arabidopsis plants grown under drought condition
by: Myint, Thawda
Published: (2013)
by: Myint, Thawda
Published: (2013)
The roles of muscle contraction and pharmaceuticals on
restoring glucose uptake in a mouse skeletal muscle
model of immobilization
by: Kirkpatrick, Euan
Published: (2024)
by: Kirkpatrick, Euan
Published: (2024)
Metabolic and functional characterisation of adult skeletal muscle in down syndrome mouse model (Ts1CJe) for insights into hypotonia in human condition
by: Lim, Chai Ling
Published: (2017)
by: Lim, Chai Ling
Published: (2017)
Exploring the role of mitochondria in the changes seen in overall skeletal muscle health associated with ageing and cancer
by: Hatt, Jacob
Published: (2021)
by: Hatt, Jacob
Published: (2021)
Consumption of omega-3 fatty acids and women's health
by: McManus, Alexandra, et al.
Published: (2013)
by: McManus, Alexandra, et al.
Published: (2013)
The effect of vitamin D on the development and function of skeletal muscle
by: Alliband, Kathryn
Published: (2024)
by: Alliband, Kathryn
Published: (2024)
The Academic Use of WhatsApp and Technostress: Investigating the Experience of Fatigue and Coping Behaviours among University Students
by: Al Abdullateef, Hafsa
Published: (2022)
by: Al Abdullateef, Hafsa
Published: (2022)
A novel puromycin decorporation method to quantify skeletal muscle protein breakdown: a proof-of-concept study
by: Crossland, Hannah, et al.
Published: (2017)
by: Crossland, Hannah, et al.
Published: (2017)
The metabolic and molecular mechanisms of hyperammonaemia and hyperethanolaemia induced protein catabolism in skeletal muscle cells
by: Crossland, Hannah, et al.
Published: (2018)
by: Crossland, Hannah, et al.
Published: (2018)
Intramyocellular lipid content and lipogenic gene expression responses following a single bout of resistance type exercise differ between young and older men
by: Tsintzas, Kostas, et al.
Published: (2017)
by: Tsintzas, Kostas, et al.
Published: (2017)
Cardiolipin is required for membrane docking of mitochondrial ribosomes and protein synthesis
by: Lee, R.G., et al.
Published: (2020)
by: Lee, R.G., et al.
Published: (2020)
Women's health care: The potential of long-chain Omega-3 polyunsaturated fatty acids
by: Hunt, W., et al.
Published: (2014)
by: Hunt, W., et al.
Published: (2014)
Metabolic and molecular changes associated with the increased skeletal muscle insulin action 24–48 h after exercise in young and old humans
by: Stephens, Francis B., et al.
Published: (2018)
by: Stephens, Francis B., et al.
Published: (2018)
The impacts of bed rest and acute trauma on muscle metabolic health in humans
by: Shur, Natalie F.
Published: (2024)
by: Shur, Natalie F.
Published: (2024)
Human skeletal muscle disuse atrophy: effects on muscle protein synthesis, breakdown and insulin resistance- a qualitative review
by: Rudrappa, Supreeth S., et al.
Published: (2016)
by: Rudrappa, Supreeth S., et al.
Published: (2016)
Effects of ageing and vitamin D deficiency on vitamin D receptor (VDR) expression in human skeletal muscle
by: Ong, Terence
Published: (2015)
by: Ong, Terence
Published: (2015)
Molecular analyses provide insight into mechanisms underlying sarcopenia and myofibre denervation in old skeletal muscles of mice
by: Barns, M., et al.
Published: (2014)
by: Barns, M., et al.
Published: (2014)
The role of skeletal muscle in the initiation and progression of knee osteoarthritis
by: Tonge, Daniel Paul
Published: (2010)
by: Tonge, Daniel Paul
Published: (2010)
Metabolic phenotyping in cells and tissues using pyruvate metabolism and nuclear magnetic resonance spectroscopy
by: Silickas, Marius
Published: (2021)
by: Silickas, Marius
Published: (2021)
Meat species identification and Halal authentication analysis using mitochondrial DNA.
by: Murugaiah, Chandrika, et al.
Published: (2009)
by: Murugaiah, Chandrika, et al.
Published: (2009)
Similar Items
-
Increasing cardiac pyruvate dehydrogenase flux during chronic hypoxia improves acute hypoxic tolerance
by: Handzlik, Michal, et al.
Published: (2018) -
Insulin resistance in health and disease: exploring the role of disuse skeletal muscle atrophy, testosterone and Beta-Hydroxy-Beta-Methylbutyrate (HMB) in young and older men
by: Shanthaveerappa Rudrappa, Supreeth
Published: (2021) -
Exploring the effects of ageing, cancer, and exercise on skeletal muscle mitochondrial function
by: Smart, Thomas
Published: (2024) -
Development of a liquid chromatography-mass spectrometry method to investigate branched chain amino acid and acylcarnitine metabolism in type 2 diabetes
by: Pabla, Pardeep
Published: (2021) -
Large-scale synthesis of both symmetrical and unsymmetrical triacylglycerols containing docosahexaenoic acid
by: Andrews, P., et al.
Published: (2008)