Randomised controlled trial of video clips and interactive games to improve vision in children with amblyopia using the I-BiT system
Background Traditional treatment of amblyopia involves either wearing a patch or atropine penalisation of the better eye. A new treatment is being developed on the basis of virtual reality technology allowing either DVD footage or computer games which present a common background to both eyes and the...
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| Format: | Article |
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BMJ Publishing Group
2016
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| Online Access: | https://eprints.nottingham.ac.uk/44957/ |
| _version_ | 1848797037912391680 |
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| author | Herbison, Nicola MacKeith, Daisy Vivian, Anthony Purdy, Jon Fakis, Apostolos Ash, Isabel M. Cobb, Sue V. Eastgate, Richard M. Haworth, Stephen M. Gregson, Richard M. Foss, Alexander J.E. |
| author_facet | Herbison, Nicola MacKeith, Daisy Vivian, Anthony Purdy, Jon Fakis, Apostolos Ash, Isabel M. Cobb, Sue V. Eastgate, Richard M. Haworth, Stephen M. Gregson, Richard M. Foss, Alexander J.E. |
| author_sort | Herbison, Nicola |
| building | Nottingham Research Data Repository |
| collection | Online Access |
| description | Background Traditional treatment of amblyopia involves either wearing a patch or atropine penalisation of the better eye. A new treatment is being developed on the basis of virtual reality technology allowing either DVD footage or computer games which present a common background to both eyes and the foreground, containing the imagery of interest, only to the amblyopic eye.
Methods A randomised control trial was performed on patients with amblyopia aged 4–8 years with three arms. All three arms had dichoptic stimulation using shutter glass technology. One arm had DVD footage shown to the amblyopic eye and common background to both, the second used a modified shooter game, Nux, with sprite and targets presented to the amblyopic eye (and background to both) while the third arm had both background and foreground presented to both eyes (non-interactive binocular treatment (non-I-BiT) games).
Results Seventy-five patients were randomised; 67 were residual amblyopes and 70 had an associated strabismus. The visual acuity improved in all three arms by approximately 0.07 logMAR in the amblyopic eye at 6 weeks. There was no difference between I-BiT DVD and non-I-BiT games compared with I-BiT games (stated primary outcome) in terms of gain in vision.
Conclusions There was a modest vision improvement in all three arms. Treatment was well tolerated and safe. There was no difference between the three treatments in terms of primary stated outcomes but treatment duration was short and the high proportion of previously treated amblyopia and strabismic amblyopia disadvantaged dichoptic stimulation treatment. |
| first_indexed | 2025-11-14T19:57:31Z |
| format | Article |
| id | nottingham-44957 |
| institution | University of Nottingham Malaysia Campus |
| institution_category | Local University |
| last_indexed | 2025-11-14T19:57:31Z |
| publishDate | 2016 |
| publisher | BMJ Publishing Group |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | nottingham-449572020-05-04T18:14:05Z https://eprints.nottingham.ac.uk/44957/ Randomised controlled trial of video clips and interactive games to improve vision in children with amblyopia using the I-BiT system Herbison, Nicola MacKeith, Daisy Vivian, Anthony Purdy, Jon Fakis, Apostolos Ash, Isabel M. Cobb, Sue V. Eastgate, Richard M. Haworth, Stephen M. Gregson, Richard M. Foss, Alexander J.E. Background Traditional treatment of amblyopia involves either wearing a patch or atropine penalisation of the better eye. A new treatment is being developed on the basis of virtual reality technology allowing either DVD footage or computer games which present a common background to both eyes and the foreground, containing the imagery of interest, only to the amblyopic eye. Methods A randomised control trial was performed on patients with amblyopia aged 4–8 years with three arms. All three arms had dichoptic stimulation using shutter glass technology. One arm had DVD footage shown to the amblyopic eye and common background to both, the second used a modified shooter game, Nux, with sprite and targets presented to the amblyopic eye (and background to both) while the third arm had both background and foreground presented to both eyes (non-interactive binocular treatment (non-I-BiT) games). Results Seventy-five patients were randomised; 67 were residual amblyopes and 70 had an associated strabismus. The visual acuity improved in all three arms by approximately 0.07 logMAR in the amblyopic eye at 6 weeks. There was no difference between I-BiT DVD and non-I-BiT games compared with I-BiT games (stated primary outcome) in terms of gain in vision. Conclusions There was a modest vision improvement in all three arms. Treatment was well tolerated and safe. There was no difference between the three treatments in terms of primary stated outcomes but treatment duration was short and the high proportion of previously treated amblyopia and strabismic amblyopia disadvantaged dichoptic stimulation treatment. BMJ Publishing Group 2016-11-01 Article PeerReviewed Herbison, Nicola, MacKeith, Daisy, Vivian, Anthony, Purdy, Jon, Fakis, Apostolos, Ash, Isabel M., Cobb, Sue V., Eastgate, Richard M., Haworth, Stephen M., Gregson, Richard M. and Foss, Alexander J.E. (2016) Randomised controlled trial of video clips and interactive games to improve vision in children with amblyopia using the I-BiT system. British Journal of Ophthalmology, 100 (11). pp. 1511-1516. ISSN 1468-2079 http://bjo.bmj.com/content/100/11/1511 doi:10.1136/bjophthalmol-2015-307798 doi:10.1136/bjophthalmol-2015-307798 |
| spellingShingle | Herbison, Nicola MacKeith, Daisy Vivian, Anthony Purdy, Jon Fakis, Apostolos Ash, Isabel M. Cobb, Sue V. Eastgate, Richard M. Haworth, Stephen M. Gregson, Richard M. Foss, Alexander J.E. Randomised controlled trial of video clips and interactive games to improve vision in children with amblyopia using the I-BiT system |
| title | Randomised controlled trial of video clips and interactive games to improve vision in children with amblyopia using the I-BiT system |
| title_full | Randomised controlled trial of video clips and interactive games to improve vision in children with amblyopia using the I-BiT system |
| title_fullStr | Randomised controlled trial of video clips and interactive games to improve vision in children with amblyopia using the I-BiT system |
| title_full_unstemmed | Randomised controlled trial of video clips and interactive games to improve vision in children with amblyopia using the I-BiT system |
| title_short | Randomised controlled trial of video clips and interactive games to improve vision in children with amblyopia using the I-BiT system |
| title_sort | randomised controlled trial of video clips and interactive games to improve vision in children with amblyopia using the i-bit system |
| url | https://eprints.nottingham.ac.uk/44957/ https://eprints.nottingham.ac.uk/44957/ https://eprints.nottingham.ac.uk/44957/ |