Ambulance-delivered transdermal glyceryl trinitrate versus sham for ultra-acute stroke: rationale, design and protocol for the Rapid Intervention with Glyceryl trinitrate in Hypertensive stroke Trial-2 (RIGHT-2) trial (ISRCTN26986053)

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Ambulance-delivered transdermal glyceryl trinitrate versus sham for ultra-acute stroke: rationale, design and protocol for the Rapid Intervention with Glyceryl trinitrate in Hypertensive stroke Trial-2 (RIGHT-2) trial (ISRCTN26986053)

Rationale: Vascular nitric oxide levels are low in acute stroke and donors such as glyceryl trinitrate have shown promise when administered very early after stroke. Potential mechanisms of action include augmentation of cerebral reperfusion, thrombolysis and thrombectomy, lowering blood pressure, an...

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Bibliographic Details
Main Authors:	Appleton, Jason P., Scutt, Polly, Dixon, Mark, Howard, Harriet, Haywood, Lee, Havard, Diane, Hepburn, Trish, England, Timothy J., Sprigg, Nikola, Woodhouse, Lisa J., Wardlaw, Joanna M., Montgomery, Alan A., Pocock, Stuart J., Bath, Philip M.W.
Format:	Article
Published:	SAGE 2017
Subjects:	Acute stroke ambulance antihypertensive therapy cerebrovascular disorders glyceryl trinitrate nitroglycerin paramedic randomized controlled trial
Online Access:	https://eprints.nottingham.ac.uk/44928/

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