Glargine and degludec: solution behaviour of higher dose synthetic insulins

QR Code

Glargine and degludec: solution behaviour of higher dose synthetic insulins

Single, double and triple doses of the synthetic insulins glargine and degludec currently used in patient therapy are characterised using macromolecular hydrodynamic techniques (dynamic light scattering and analytical ultracentrifugation) in an attempt to provide the basis for improved personalised...

Full description

Bibliographic Details
Main Authors:	Adams, Gary G., Alzahrani, Qushmua, Jiwani, Shahwar I., Meal, Andrew, Morgan, Paul S., Coffey, Frank, Kok, Samil, Rowe, Arthur J., Harding, Stephen E., Chayen, Naomi, Gillis, Richard B.
Format:	Article
Published:	Nature Publishing Group 2017
Subjects:	Diabetes complications; Protein delivery
Online Access:	https://eprints.nottingham.ac.uk/44848/

Similar Items

Characterisation of insulin analogues therapeutically available to patients
by: Adams, Gary G., et al.
Published: (2018)

Transdermal insulin on demand
by: Smith, Fiona
Published: (2024)

Effect of thymoquinone and thymoquinone-loaded nanostructured lipid carrier in in vitro wound healing model
by: Alexander, Henna Roshini
Published: (2019)

Risk factors of tuberculosis among diabetes mellitus patients in Hospital Sultanah Bahiyah, Alor Setar 2015-2016
by: Fauzi, Farah Fatin
Published: (2017)

The relationship between low blood thiamin levels in diabetes to thiamin intake and diabetic control
by: Vindedzis, Sally Ann
Published: (2008)

Hydrodynamic characterisation of therapeutic glycan and glycan-like complexes
by: Alzahrani, Qushmua Eidan
Published: (2017)

Obstetric Complications and Psychological Well-being: Experiences of Bangladeshi Women during Pregnancy and Childbirth
by: Gausia, K., et al.
Published: (2012)

Development of a footcare education intervention delivered by community health workers to Type 2 diabetes patients
by: Okatiranti, Okatiranti
Published: (2024)

Some mechanisms for wound healing enhancing effects of bitter gourd (Momordica charantia L.) extract in diabetic rats
by: Rezaeizadeh, Alireza
Published: (2013)

Obstetric complications and cesarean delivery in Nepal
by: Karkee, Rajendra, et al.
Published: (2014)

Nutrient regulation of insulin secretion and action
by: Newsholme, Philip, et al.
Published: (2014)

Ultracentrifuge methods for the analysis of polysaccharides, glycoconjugates, and lignins
by: Harding, Stephen E., et al.
Published: (2015)

Metabolic signature in stage A/B heart failure: A study in asymptomatic Type 2 Diabetes
by: Brady, Emer M.
Published: (2024)

Factors associated with cardiovascular disease in patients with type 2 diabetes mellitus
by: Tan, Mun Chieng
Published: (2013)

Comparison of GIP and GLP-1 promoter-mediated insulin expression in Gut K and L-cells for the potential treatment of diabetes mellitus
by: Rasouli, Mina
Published: (2012)

PEDF-induced alteration of metabolism leading to insulin resistance
by: Carnagarin, Revathy, et al.
Published: (2015)

Effect of interpregnancy interval on gestational diabetes: a retrospective matched cohort study
by: Gebremedhin, Amanuel Tesfay, et al.
Published: (2019)

Cardiovascular and metabolic outcomes associated with insulin use in type 2 diabetes: evidence from insulin users in the UK primary care
by: Anyanwagu, Uchenna Chidi
Published: (2017)

A novel analytical ultracentrifugation based approach to the low resolution structure of gum arabic
by: Gillis, Richard B., et al.
Published: (2016)

The novel application of chitosan for the intranasal delivery of insulin
by: Hinchcliffe, Michael
Published: (1996)

Developing an Oral-Insulin-Delivery System using GET-peptide-mediated transcytosis
by: Rehmani, Sahrish
Published: (2021)

The occurrence and risk factors for first venous thromboembolism in and around pregnancy: population based cohort studies using primary and secondary care data from the United Kingdom
by: Abdul Sultan, Alyshah
Published: (2013)

Effect of Diet, Insulin and Exercise on the Regulation of Carbohydrate Metabolism in Health and Type 1 Diabetes
by: Chokkalingam, Kamalakkannan
Published: (2007)

The enhancement of insulin sensitivity by stevioside from Stevia rebaudiana Bertoni in in vitro and in silico models / Nabilatul Hani Mohd Radzman
by: Mohd Radzman, Nabilatul Hani
Published: (2018)

Hydrodynamic characterisation of macromolecules in cucurbits
by: Jiwani, Shahwar
Published: (2016)

The relationship between urinary albumin excretion, cardiovascular outcomes and total mortality among a large cohort of insulin-treated patients with type 2 diabetes in routine primary care practices
by: Anyanwagu, Uchenna Chidi, et al.
Published: (2018)

Alzheimer's beta-amyloid peptides compete for insulin binding to the insulin receptor
by: Xie, Ling, et al.
Published: (2002)

Simple psoas cross-sectional area measurement is a quick and easy method to assess sarcopenia and predicts major surgical complications
by: Jones, K.I., et al.
Published: (2015)

Relationship between learning ability and genotoxicity from organophosphate pesticide exposure among primary school children in Tanjung Karang, Selangor, Malaysia
by: Miswon, Nurul Husna
Published: (2016)

Nutritional status and pregnancy outcomes between anaemic and non anaemic pregnant women in Hulu Selangor, Malaysia
by: Zalbahar @ Zabaha, Nurzalinda
Published: (2009)

Expression profiling of diabetic and hypertension-associated genes of Malaysian male subjects with coronary heart disease in a hospital in Malaysia
by: Ahmadloo, Salma
Published: (2017)

Spatiotemporal trends and risk factors of unsuccessful treatment outcomes among tuberculosis patients in Selangor, Malaysia
by: Kaur, Kirandeep Kulwant
Published: (2021)

Formulation and characterization of anti-atherosclerosis drug loaded liquid crystalline nanoparticle
by: Maslizan, Mardhiah
Published: (2022)

A systematic review and meta-analysis of patient education in preventing and reducing the incidence or recurrence of adult diabetes foot ulcers (DFU)
by: Adiewere, P., et al.
Published: (2018)

A review of modern approaches to the hydrodynamic characterisation of polydisperse macromolecular systems in biotechnology
by: Gillis, Richard B., et al.
Published: (2015)

Diabetic foot screening: why is it neglected?
by: Abu-Qamar, Ma'en
Published: (2006)

Development of a glucose sensitive insulin delivery PLGA microparticle system
by: Dino, Mohamad Hadid Amshah
Published: (2018)

Glycemic control among insulin-treated Type 2 diabetes in Kelantan
by: Ismail, Adibah Hanim, et al.
Published: (2016)

Matrix-free hydrodynamic study on the size distribution and conformation of three technical lignins from wood and non-wood
by: Alzahrani, Qushmua E., et al.
Published: (2016)

Does teenage pregnancy and childbirth really increase risk?: exploring outcomes through secondary analysis of NHS data
by: Watts, Kim
Published: (2010)