Simple psoas cross-sectional area measurement is a quick and easy method to assess sarcopenia and predicts major surgical complications

Aim Radiologically assessed muscle mass has been suggested as a surrogate marker of functional status and frailty and may predict patients at risk of postoperative complications. We hypothesize that sarcopenia negatively impacts on postoperative recovery and is predictive of complications. Metho...

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Main Authors: Jones, K.I., Doleman, Brett, Scott, S.D., Lund, Jonathan N., Williams, John P.
Format: Article
Published: Wiley 2015
Subjects:
Online Access:https://eprints.nottingham.ac.uk/44535/
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author Jones, K.I.
Doleman, Brett
Scott, S.D.
Lund, Jonathan N.
Williams, John P.
author_facet Jones, K.I.
Doleman, Brett
Scott, S.D.
Lund, Jonathan N.
Williams, John P.
author_sort Jones, K.I.
building Nottingham Research Data Repository
collection Online Access
description Aim Radiologically assessed muscle mass has been suggested as a surrogate marker of functional status and frailty and may predict patients at risk of postoperative complications. We hypothesize that sarcopenia negatively impacts on postoperative recovery and is predictive of complications. Method One hundred patients undergoing elective resection for colorectal carcinoma were included in this study. Lean muscle mass was estimated by measuring the cross-sectional area of the psoas muscle at the level of the third lumbar vertebra identified on a preoperative CT scan, normalizing for patient height. Perioperative morbidity was scored according to the Clavien–Dindo classification. All statistical data analyses were carried out using the Statistical Package for the Social Sciences (SPSS) version 20.0. Results Fifteen per cent of patients were identified as sarcopenic. There were no deaths in the study group. Sarcopenia was associated with a significantly increased risk of developing major complications (Grade 3 or greater, OR = 5.41, 95% CI: 1.45–20.15, P = 0.01). Sarcopenia did not predict length of stay, critical care dependency or time to mobilization. Conclusion Sarcopenia, as a marker of frailty, is an important risk factor in surgical patients but difficult to estimate using bedside testing. CT scans, performed for preoperative staging, provide an opportunity to quantify lean muscle mass without additional cost or exposure to radiation and eliminate the inconvenience of further investigations.
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spelling nottingham-445352020-05-04T20:10:17Z https://eprints.nottingham.ac.uk/44535/ Simple psoas cross-sectional area measurement is a quick and easy method to assess sarcopenia and predicts major surgical complications Jones, K.I. Doleman, Brett Scott, S.D. Lund, Jonathan N. Williams, John P. Aim Radiologically assessed muscle mass has been suggested as a surrogate marker of functional status and frailty and may predict patients at risk of postoperative complications. We hypothesize that sarcopenia negatively impacts on postoperative recovery and is predictive of complications. Method One hundred patients undergoing elective resection for colorectal carcinoma were included in this study. Lean muscle mass was estimated by measuring the cross-sectional area of the psoas muscle at the level of the third lumbar vertebra identified on a preoperative CT scan, normalizing for patient height. Perioperative morbidity was scored according to the Clavien–Dindo classification. All statistical data analyses were carried out using the Statistical Package for the Social Sciences (SPSS) version 20.0. Results Fifteen per cent of patients were identified as sarcopenic. There were no deaths in the study group. Sarcopenia was associated with a significantly increased risk of developing major complications (Grade 3 or greater, OR = 5.41, 95% CI: 1.45–20.15, P = 0.01). Sarcopenia did not predict length of stay, critical care dependency or time to mobilization. Conclusion Sarcopenia, as a marker of frailty, is an important risk factor in surgical patients but difficult to estimate using bedside testing. CT scans, performed for preoperative staging, provide an opportunity to quantify lean muscle mass without additional cost or exposure to radiation and eliminate the inconvenience of further investigations. Wiley 2015-01 Article PeerReviewed Jones, K.I., Doleman, Brett, Scott, S.D., Lund, Jonathan N. and Williams, John P. (2015) Simple psoas cross-sectional area measurement is a quick and easy method to assess sarcopenia and predicts major surgical complications. Colorectal Disease, 17 (1). O20-O26. ISSN 1463-1318 Sarcopenia; complications; computed tomography http://onlinelibrary.wiley.com/doi/10.1111/codi.12805/abstract doi:10.1111/codi.12805 doi:10.1111/codi.12805
spellingShingle Sarcopenia; complications; computed tomography
Jones, K.I.
Doleman, Brett
Scott, S.D.
Lund, Jonathan N.
Williams, John P.
Simple psoas cross-sectional area measurement is a quick and easy method to assess sarcopenia and predicts major surgical complications
title Simple psoas cross-sectional area measurement is a quick and easy method to assess sarcopenia and predicts major surgical complications
title_full Simple psoas cross-sectional area measurement is a quick and easy method to assess sarcopenia and predicts major surgical complications
title_fullStr Simple psoas cross-sectional area measurement is a quick and easy method to assess sarcopenia and predicts major surgical complications
title_full_unstemmed Simple psoas cross-sectional area measurement is a quick and easy method to assess sarcopenia and predicts major surgical complications
title_short Simple psoas cross-sectional area measurement is a quick and easy method to assess sarcopenia and predicts major surgical complications
title_sort simple psoas cross-sectional area measurement is a quick and easy method to assess sarcopenia and predicts major surgical complications
topic Sarcopenia; complications; computed tomography
url https://eprints.nottingham.ac.uk/44535/
https://eprints.nottingham.ac.uk/44535/
https://eprints.nottingham.ac.uk/44535/