A European randomised controlled trial of the addition of etoposide to standard vincristine and carboplatin induction as part of an 18-month treatment programme for childhood (≤16 years) low grade glioma: a final report

A European randomised controlled trial of the addition of etoposide to standard vincristine and carboplatin induction as part of an 18-month treatment programme for childhood (≤16 years) low grade glioma: a final report

Background The use of chemotherapy to manage newly diagnosed low grade glioma (LGG) was first introduced in the 1980s. One randomised trial has studied two- versus four-drug regimens with a duration of 12 months of treatment after resection. Methods Within the European comprehensive treatme...

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Bibliographic Details
Main Authors: Gnekow, Astrid K., Walker, David A., Kandels, Daniela, Picton, Susan, Perilongo, Giorgio, Grill, Jacques, Stokland, Tore, Sandstrom, Per Eric, Warmuth-Metz, Monika, Pietsch, Torsten, Giangaspero, Felice, Schmidt, René, Faldum, Andreas, Kilmartin, Denise, De Paoli, Angela, De Salvo, Gian Luca
Format: Article
Published: Elsevier 2017
Subjects:
Low grade glioma; Childhood; Chemotherapy; Randomised trial
Online Access:https://eprints.nottingham.ac.uk/44511/

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