Assessment of the protein interaction between coagulation factor XII and corn trypsin inhibitor by molecular docking and biochemical validation
Background: Corn trypsin inhibitor (CTI) has selectivity for serine proteases coagulation factor XII (FXII) and trypsin. CTI is in widespread use as a reagent that specifically inhibits the intrinsic pathway of blood coagulation but not the extrinsic pathway. Objectives: To investigate the molecu...
| Main Authors: | , , , , , |
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| Format: | Article |
| Published: |
Wiley
2017
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| Subjects: | |
| Online Access: | https://eprints.nottingham.ac.uk/44393/ |