Molecular mechanisms underlying variations in lung function: a systems genetics analysis

Molecular mechanisms underlying variations in lung function: a systems genetics analysis

Background: Lung function measures reflect the physiological state of the lung, and are essential to the diagnosis of chronic obstructive pulmonary disease (COPD). The SpiroMeta-CHARGE consortium undertook the largest genome wide association study (GWAS) so far (n=48 201) for forced expiratory volum...

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Main Authors: Obeidat, Ma'en, Hao, Ke, Bossé, Yohan, Nickle, David C., Nie, Yunlong, Postma, Dirkje S., Laviolette, Michel, Sandford, Andrew J., Daley, Denise D., Hogg, James C., Elliott, W. Mark, Fishbane, Nick, Timens, Wim, Hysi, Pirro G., Kaprio, Jaakko, Wilson, James F., Hui, Jennie, Rawal, Rajesh, Schulz, Holger, Stubbe, Beate, Hayward, Caroline, Polasek, Ozren, Järvelin, Marjo-Riitta, Zhao, Jing Hua, Jarvis, Deborah, Kähönen, Mika, Franceschini, Nora, North, Kari E., Loth, Daan W., Brusselle, Guy G., Smith, Albert Vernon, Gudnason, Vilmundur, Bartz, Traci M, Wilk, Jemma B., O'Connor, George T., Cassano, Patricia A., Tang, Wenbo, Wain, Louise V., Artigas, María Soler, Gharib, Sina A., Strachan, David P., Sin, Don D., Tobin, Martin D., London, Stephanie J., Hall, Ian P., Paré, Peter D.
Format: Article
Published: Elsevier 2015
Online Access:https://eprints.nottingham.ac.uk/44364/

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