Human placental renin–angiotensin system in normotensive and pre-eclamptic pregnancies at high altitude and after acute hypoxia–reoxygenation insult

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Human placental renin–angiotensin system in normotensive and pre-eclamptic pregnancies at high altitude and after acute hypoxia–reoxygenation insult

A functioning placental renin–angiotensin system (RAS) appears necessary for uncomplicated pregnancy and is present during placentation, which occurs under low oxygen tensions. Placental RAS is increased in pre-eclampsia (PE), characterised by placental dysfunction and elevated oxidative stress. We...

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Bibliographic Details
Main Authors:	Kurlak, L.O., Mistry, Hiten D., Cindrova-Davies, Tereza, Burton, Graham, Broughton Pipkin, Fiona
Format:	Article
Published:	Wiley 2016
Subjects:	renin-angiotensin system; hypoxia placenta; hypoxia-re-oxygenation; hypoxia-inducible factors
Online Access:	https://eprints.nottingham.ac.uk/44333/

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