Placental expression of adenosine A2A receptor and hypoxia inducible factor-1 alpha in early pregnancy, term and pre-eclamptic pregnancies: interactions with placental renin-angiotensin system

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Placental expression of adenosine A2A receptor and hypoxia inducible factor-1 alpha in early pregnancy, term and pre-eclamptic pregnancies: interactions with placental renin-angiotensin system

Normal placentation occurs under low oxygen tensions yet hypoxia is also implicated in placental pathologies such as pre-eclampsia (PE). Hypoxia-inducible factors (HIFs), adenosine and tissue renin-angiotensin-system (RAS) are known to promote angiogenesis and vascularisation. We hypothesised that...

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Bibliographic Details
Main Authors:	Kurlak, L.O., Williams, Paula Juliet, Bulmer, Judith N., Broughton Pipkin, Fiona, Mistry, Hiten D.
Format:	Article
Published:	Elsevier 2015
Subjects:	Placental A2AR; HIF-1α: angiotensin receptors; Early pregnancy; Pre-eclampsia
Online Access:	https://eprints.nottingham.ac.uk/44329/

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