Antidepressants are cytotoxic to rat primary blood brain barrier endothelial cells at high therapeutic concentrations

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Antidepressants are cytotoxic to rat primary blood brain barrier endothelial cells at high therapeutic concentrations

Antidepressants are commonly employed for the treatment of major depressive disorders and other psychiatric conditions. We investigated the relatively acute cytotoxic effects of three commonly prescribed antidepressants: fluoxetine, sertraline, and clomipramine on rat primary blood brain barrier end...

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Bibliographic Details
Main Authors:	Elmorsy, Ekramy, Al-Ghafari, Ayat, Almutairi, Fahd M., Aggour, Amal Misbah, Carter, Wayne
Format:	Article
Published:	Elsevier 2017
Subjects:	Antidepressants; Blood brain barrier; Cytotoxicity; Oxidative stress; Genotoxicity; Antioxidants
Online Access:	https://eprints.nottingham.ac.uk/44278/

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