High prevalence of subclass-specific binding and neutralizing antibodies against Clostridium difficile toxins in adult cystic fibrosis sera: possible mode of immunoprotection against symptomatic C. difficile infection

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High prevalence of subclass-specific binding and neutralizing antibodies against Clostridium difficile toxins in adult cystic fibrosis sera: possible mode of immunoprotection against symptomatic C. difficile infection

Objectives: Despite multiple risk factors and a high rate of colonization for Clostridium difficile, the occurrence of C. difficile infection in patients with cystic fibrosis is rare. The aim of this study was to compare the prevalence of binding C. difficile toxin-specific immunoglobulin (Ig)A, IgG...

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Bibliographic Details
Main Authors:	Monaghan, Tanya M., Negm, Ola H., MacKenzie, B., Hamed, Mohamed R., Shone, Clifford C., Humphreys, D.P., Acharya, K. Ravi, Wilcox, Mark H.
Format:	Article
Published:	Dove Medical Press 2017
Subjects:	Clostridium difficile Cystic fibrosis Antibodies
Online Access:	https://eprints.nottingham.ac.uk/44230/

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