Thecal cell sensitivity to luteinizing hormone and insulin in polycystic ovarian syndrome

QR Code

Thecal cell sensitivity to luteinizing hormone and insulin in polycystic ovarian syndrome

This study examined whether a defect of steroid synthesis in ovarian theca cells may lead to the development of PCOS, through contributions to excess androgen secretion. Polycystic ovarian syndrome (PCOS) is one of the leading causes of infertility worldwide affecting around 1 in 10 of women of a...

Full description

Bibliographic Details
Main Authors:	Cadagan, David, Khan, Raheela, Amer, Saad A.
Format:	Article
Published:	Elsevier 2016
Subjects:	17α-Hydroxylase Androgen Insulin Luteinizing hormone Theca
Online Access:	https://eprints.nottingham.ac.uk/44223/

Similar Items

Investigating Molecular Interactions of Thyroid Hormone and Androgen Receptors
by: Zhao, Yi
Published: (2023)

Ontogeny and nutritional programming of the hepatic growth hormone-insulin-like growth factor-prolactin axis in the sheep
by: Hyatt, M.A., et al.
Published: (2007)

Cryptorchidism in the orl rat is associated with muscle patterning defects in the fetal gubernaculum and altered hormonal signaling
by: Barthold, Julia S., et al.
Published: (2014)

Longitudinal assessment of circulating insulin-like peptide 3 levels in healthy peripubertal girls
by: Hagen, Casper P., et al.
Published: (2015)

Gene expression of inflammatory markers in adipose tissue between obese women with polycystic ovary and normal obese women
by: Alshammari, G., et al.
Published: (2017)

Exposure to non-kin females rapidly affects testicular morphology in non-reproductive male Damaraland mole-rats
by: Nice, P., et al.
Published: (2010)

Three-dimensional image analysis to quantify the temporo-spacial expression of cellular receptors
by: Almahbobi, Ghanim, et al.
Published: (2013)

The molecular mechanism of insulin action in human theca and adipocyte cells in polycycstic ovarian syndrome
by: Cadagan, David
Published: (2013)

Polycystic ovarian syndrome and adipose tissue: contribution of peripheral androgen synthesis to hyperandrogenism in polycystic ovarian syndrome
by: Alzanati, Nadia
Published: (2017)

Theca cell INSL3 and steroids together orchestrate the growing bovine antral follicle
by: Dai, Yanzhenzi, et al.
Published: (2017)

Raising awareness on polycystic ovarian syndrome
by: Manickam, Deepalakshmi
Published: (2025)

Epitranscriptomic Determinants of Aggressive Prostate Cancer
by: Haigh, Daisy
Published: (2021)

Nutrient regulation of insulin secretion and action
by: Newsholme, Philip, et al.
Published: (2014)

The influence of circulating anti-Müllerian hormone on ovarian responsiveness to ovulation induction with gonadotrophins in women with polycystic ovarian syndrome: a pilot study
by: Amer, Saad A., et al.
Published: (2013)

Comparison of fecal hormone extraction methods and analysis on reproductive hormones in female Malayan tapirs
by: Ruslan, Muhammad Najib
Published: (2018)

Alzheimer's beta-amyloid peptides compete for insulin binding to the insulin receptor
by: Xie, Ling, et al.
Published: (2002)

The effect of metformin on the metabolic parameters in polycystic ovarian syndrome.
by: Dahlia Abd Malik,, et al.
Published: (2014)

Review on automated follicle identification for polycystic ovarian syndrome
by: Nazarudin, A. A., et al.
Published: (2020)

The effects of cannabinoids on insulin secretion
by: Anderson, Richard L.
Published: (2011)

Hormonal regulation of mango fruit ripening
by: Sakimin, Siti Zaharah
Published: (2011)

Mechanisms underlying obesity-related insulin resistance
by: Tewari, Nilanjana
Published: (2016)

Androgens and the endometrium
by: Suri, Narinder K.
Published: (1988)

The impact of excision of benign nonendometriotic ovarian cysts on ovarian reserve: a systematic review
by: Mohamed, Ahmed A., et al.
Published: (2016)

Protein and Hormone Profiling of Hormone-Treated or Untreated Excised Oil Palm (Elaeis Guineensis Jacq.) Spear Leaves
by: Mohamed Ramly, Halina
Published: (2010)

Ficus deltoidea ethanolic leaves extract improves hormonal balance among letrozole induced polycystic ovarian syndrome (PCOS) rats
by: Nur Ajeerah Suhaimi,, et al.
Published: (2017)

Nutritional Regulation of Insulin Secretion: Implications for Diabetes
by: Newsholme, Philip, et al.
Published: (2012)

The Role of Luteinizing Hormone in Alzheimer’s Disease
by: Barron, A., et al.
Published: (2010)

Evaluation of cell-penetrating peptides as tools to improve nose-brain delivery of insulin
by: Brown, Alexander
Published: (2024)

PEDF-induced alteration of metabolism leading to insulin resistance
by: Carnagarin, Revathy, et al.
Published: (2015)

The mechanistic basis of metabolic response to surgery and postoperative insulin resistance in patients having abdominal surgery
by: Varadhan, Krishna Kumar
Published: (2015)

Endocrine and immune responses to resistance training in prostate cancer patients
by: Galvao, D, et al.
Published: (2008)

Novel gonadal characteristics in an aged bovine freemartin
by: Remnant, J.G., et al.
Published: (2014)

Influence of dietary polyunsaturated fatty acids on glucose sensitivity, insulin resistance and cognitive function in a rat model
by: Tan, Ai Li
Published: (2014)

Insulin-like peptide 3 (INSL3) is a major regulator of female reproductive physiology
by: Anand-Ivell, Ravinder, et al.
Published: (2018)

Prevalence and correlates of polycystic ovarian syndrome among women attending infertility clinic
by: Tusimin, Maiza, et al.
Published: (2018)

Effect of exercise and weight loss in polycystic ovarian syndrome among obese women
by: Cochrane, Thomas, et al.
Published: (2021)

Cardiovascular and metabolic outcomes associated with insulin use in type 2 diabetes: evidence from insulin users in the UK primary care
by: Anyanwagu, Uchenna Chidi
Published: (2017)

Structure and function of the insulin receptor: its role during lactation and foetal development
by: Deleo, Domenica
Published: (1994)

Amino acid modulation of gut hormone release and defining roles of GLP-1 and insulin in muscle microcirculation and metabolism in older age
by: Abdulla, Haitham M.A.
Published: (2018)

Ovarian reserve after salpingectomy: a systematic review and meta-analysis
by: Mohamed, Ahmed Aboelfadle, et al.
Published: (2017)