The impact of detergents on the tissue decellularization process: a ToF-SIMS study

QR Code

The impact of detergents on the tissue decellularization process: a ToF-SIMS study

Biologic scaffolds are derived from mammalian tissues, which must be decellularized to remove cellular antigens that would otherwise incite an adverse immune response. Although widely used clinically, the optimum balance between cell removal and the disruption of matrix architecture and surface liga...

Full description

Bibliographic Details
Main Authors:	White, Lisa J., Taylor, Adam J., Faulk, Denver M., Keane, Timothy J., Saldin, Lindsey T., Reing, Janet E., Swinehart, Ilea T., Turner, Neill J., Ratner, Buddy D., Badylak, Stephen F.
Format:	Article
Published:	Elsevier 2017
Subjects:	extracellular matrix biologic scaffold decellularization ToF-SIMS detergents
Online Access:	https://eprints.nottingham.ac.uk/44203/

Similar Items

The development of ToF-SIMS for in-situ glycosaminoglycan analysis
by: Milne, Lorna
Published: (2025)

Extracellular matrix hydrogels from decellularized tissues: structure and function
by: Saldin, Lindsey T., et al.
Published: (2017)

3D ToF-SIMS imaging of polymer multilayer films using argon cluster sputter depth profiling
by: Bailey, James, et al.
Published: (2015)

Probing the distribution of pharmaceutical compounds in cells using ToF-SIMS
by: Newman, Carla A.F. Fernandes
Published: (2019)

Novel Applications of FIB-SEM-Based ToF-SIMS in Atom Probe Tomography Workflows
by: Rickard, William, et al.
Published: (2020)

To F-SIMS/XPS chemical depth profiling of synthetic polymer hydrogels
by: Taylor, Michael
Published: (2017)

Detergency Studies of Protease F1
by: Thekkamalai, Gunasekaran
Published: (1996)

On the suitability of high vacuum electrospray deposition for the fabrication of molecular electronic devices
by: Temperton, Robert H., et al.
Published: (2017)

Decellularized bone extracellular matrix and human dental pulp stem cells as a construct for bone regeneration
by: Paduano, Francesco, et al.
Published: (2017)

Age-related changes to human stratum corneum lipids detected using time-of-flight secondary ion mass spectrometry following in vivo sampling
by: Starr, Nichola J., et al.
Published: (2016)

Quantification and qualitative effects of different PEGylations on Poly(butyl cyanoacrylate) nanoparticles
by: Aslund, Andreas K.O, et al.
Published: (2017)

High throughput discovery of thermo-responsive materials using water contact angle measurements and time-of-flight secondary ion mass spectrometry
by: Hook, Andrew L., et al.
Published: (2013)

NanoSIMS investigation of passive oxide films on high-Cr cast iron
by: Salasi, Mobin, et al.
Published: (2013)

Macrophage phenotype in response to ECM bioscaffolds
by: Huleihel, Luai, et al.
Published: (2017)

The effect of grain orientation on secondary ion mass spectrometry (SIMS) analysis of rutile
by: Taylor, Rich, et al.
Published: (2012)

Fabrication and Evaluation of Electrospun Silk Fibroin/Halloysite Nanotube Biomaterials for Soft Tissue Regeneration
by: Mohammadzadehmoghadam, Soheila, et al.
Published: (2022)

Enabling in situ protein analysis for pharmaceutical applications using 3D OrbiSIMS
by: Kotowska, Anna
Published: (2022)

Restoring mucosal barrier function and modifying macrophage phenotype with an extracellular matrix hydrogel: potential therapy for ulcerative colitis
by: Keane, Timothy J., et al.
Published: (2017)

Development of in vitro screening approaches to optimise formulation performance.
by: Gallas, Andrzej
Published: (2014)

Self-reporting scaffolds for in situ monitoring for regenerative medicine and tissue engineering applications
by: Ahmed, Shehnaz
Published: (2018)

Investigating ApoE4-Mediated Molecular Alterations in H4 Neuroglioma Cells of Alzheimer’s Disease Using OrbiSIMS and LC-MS/MS.
by: Lu, Li
Published: (2025)

An injectable degradable porous polymer scaffold for tissue engineering and drug delivery
by: Salem, Aliasger K.
Published: (2002)

Uncovering the molecular compositions, origins and formation pathways of engine deposits using OrbiSIMS
by: Edney, Max
Published: (2022)

Forage yield and quality of kenaf (Hibiscus cannabinus L.) for consumption as ruminant feed
by: Noori, Zahra, et al.
Published: (2016)

A novel method for the fabrication of porous Poly-Ether-Ether-Ketone using sodium chloride as a porogen
by: Siddiq, Abdur Rahman
Published: (2016)

Multivariate ToF-SIMS image analysis of polymer microarrays and protein adsorption
by: Hook, Andrew L., et al.
Published: (2015)

Matrix-free laser desorption/ionisation mass spectrometry on rough or porous semiconductor substrates: theory and applications
by: Law, Kai
Published: (2008)

Formulation and characterization of surface functionalized PLGA based microparticles for in vitro stem cell survival
by: Uğur, Deniz
Published: (2019)

Comparative proteomic analysis on fruit ripening processes in two varieties of tropical mango (Mangifera indica)
by: Chin, Chiew Foan, et al.
Published: (2019)

Configuarable and flexible immersive learning environment: An enhanced solution for the OpenSim platform to support end-users
by: Guetl, Christian, et al.
Published: (2013)

Understanding astrocyte-derived extracellular vesicles in health and disease
by: White, Katherine
Published: (2024)

Recovery of extracellular lipase from burkholderia sp. st8 in aqueous two-phase systems
by: Ooi, Chien Wei
Published: (2011)

Using SimCLIM for Modelling the Impacts of Climate Extremes in a Changing Climate: A Preliminary Case Study of Household Water Harvesting in Southeast Queensland
by: Warrick, Richard
Published: (2009)

Porous scaffolds and soft hydrogel scaffolds for soft tissue engineering
by: Yang, Yang
Published: (2018)

Spatial risk-based assessments for climate adaptation using the SimCLIM modelling system: a case study of domestic rainwater harvesting as the sole source of water
by: Warrick, Richard, et al.
Published: (2012)

Nondestructive Localization of Surface Particles for Elemental Compositional Analysis by TOF-SIMS
by: Lee, Wah-Pheng, et al.
Published: (2005)

OpenSimRoot: widening the scope and application of root architectural models
by: Postma, Johannes A., et al.
Published: (2017)

Novel insights into ascorbic acid skin permeation
by: Mistry, Jatin
Published: (2020)

Retagging identifies dendritic cell-specific intercellular adhesion molecule-3 (ICAM3)-grabbing non-integrin (DC-SIGN) protein as a novel receptor for a major allergen from house dust mite
by: Emara, Mohamed, et al.
Published: (2012)

A complex interplay between the extracellular matrix and the innate immune response to microbial pathogens
by: Tomlin, Hannah, et al.
Published: (2018)