Klinefelter’s Syndrome and sexual offending: a literature review

Background: Klinefelter’s Syndrome is a sex chromosome abnormality affecting approximately 1 in 1000 males. There have been suggestions that it is associated with a higher than average prevalence of sexual offending but to what extent does research evidence support this assertion? Aims: To conduct...

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Main Authors: O'Donovan, Rebecca, Völlm, Birgit
Format: Article
Published: John Wiley & Sons, Ltd 2017
Online Access:https://eprints.nottingham.ac.uk/44120/
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author O'Donovan, Rebecca
Völlm, Birgit
author_facet O'Donovan, Rebecca
Völlm, Birgit
author_sort O'Donovan, Rebecca
building Nottingham Research Data Repository
collection Online Access
description Background: Klinefelter’s Syndrome is a sex chromosome abnormality affecting approximately 1 in 1000 males. There have been suggestions that it is associated with a higher than average prevalence of sexual offending but to what extent does research evidence support this assertion? Aims: To conduct a systematic review of published research to establish the prevalence of sexual offending in males with Klinefelter’s Syndrome. Method: The databases MEDLINE, PsycINFO and EMBASE were searched from inception until 31st December 2016 using a range of terms for Klinefelter’s syndrome and for sexual offending. All selected papers were examined for quality using the STROBE (Strengthening of Observational Studies in Epidemiology) checklist. Results: We identified 53 relevant papers of which ten met our inclusion criteria. All but one were prevalence studies conducted in a prison or hospital setting. The one, Danish, register based cohort study did suggest an increased risk of sex offending among Klinefelter men, probably established before the diagnosis was made and, therefore, any hormone replacement instituted. Conclusion: There is insufficient evidence to date to support concerns about exceptional risk of sex offending among men with Klinefelter’s syndrome. Rather, it is arguable that there is a research gap in understanding how the experience of and treatment for their condition may affect them.
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spelling nottingham-441202020-05-04T18:59:43Z https://eprints.nottingham.ac.uk/44120/ Klinefelter’s Syndrome and sexual offending: a literature review O'Donovan, Rebecca Völlm, Birgit Background: Klinefelter’s Syndrome is a sex chromosome abnormality affecting approximately 1 in 1000 males. There have been suggestions that it is associated with a higher than average prevalence of sexual offending but to what extent does research evidence support this assertion? Aims: To conduct a systematic review of published research to establish the prevalence of sexual offending in males with Klinefelter’s Syndrome. Method: The databases MEDLINE, PsycINFO and EMBASE were searched from inception until 31st December 2016 using a range of terms for Klinefelter’s syndrome and for sexual offending. All selected papers were examined for quality using the STROBE (Strengthening of Observational Studies in Epidemiology) checklist. Results: We identified 53 relevant papers of which ten met our inclusion criteria. All but one were prevalence studies conducted in a prison or hospital setting. The one, Danish, register based cohort study did suggest an increased risk of sex offending among Klinefelter men, probably established before the diagnosis was made and, therefore, any hormone replacement instituted. Conclusion: There is insufficient evidence to date to support concerns about exceptional risk of sex offending among men with Klinefelter’s syndrome. Rather, it is arguable that there is a research gap in understanding how the experience of and treatment for their condition may affect them. John Wiley & Sons, Ltd 2017-08-07 Article PeerReviewed O'Donovan, Rebecca and Völlm, Birgit (2017) Klinefelter’s Syndrome and sexual offending: a literature review. Criminal Behaviour and Mental Health, 28 (2). pp. 132-140. ISSN 1471-2857 http://onlinelibrary.wiley.com/doi/10.1002/cbm.2052/full doi:10.1002/cbm.2052 doi:10.1002/cbm.2052
spellingShingle O'Donovan, Rebecca
Völlm, Birgit
Klinefelter’s Syndrome and sexual offending: a literature review
title Klinefelter’s Syndrome and sexual offending: a literature review
title_full Klinefelter’s Syndrome and sexual offending: a literature review
title_fullStr Klinefelter’s Syndrome and sexual offending: a literature review
title_full_unstemmed Klinefelter’s Syndrome and sexual offending: a literature review
title_short Klinefelter’s Syndrome and sexual offending: a literature review
title_sort klinefelter’s syndrome and sexual offending: a literature review
url https://eprints.nottingham.ac.uk/44120/
https://eprints.nottingham.ac.uk/44120/
https://eprints.nottingham.ac.uk/44120/