Multiple species comparison of cardiac troponin T and dystrophin: unravelling the DNA behind dilated cardiomyopathy
Animals have frequently been used as models for human disorders and mutations. Following advances in genetic testing and treatment options, and the decreasing cost of these technologies in the clinic, mutations in both companion and commercial animals are now being investigated. A recent review high...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Published: |
MDPI
2017
|
| Subjects: | |
| Online Access: | https://eprints.nottingham.ac.uk/44092/ |
| _version_ | 1848796835937779712 |
|---|---|
| author | England, Jennifer Loughna, Siobhan Rutland, Catrin S. |
| author_facet | England, Jennifer Loughna, Siobhan Rutland, Catrin S. |
| author_sort | England, Jennifer |
| building | Nottingham Research Data Repository |
| collection | Online Access |
| description | Animals have frequently been used as models for human disorders and mutations. Following advances in genetic testing and treatment options, and the decreasing cost of these technologies in the clinic, mutations in both companion and commercial animals are now being investigated. A recent review highlighted the genes associated with both human and non-human dilated cardiomyopathy. Cardiac troponin T and dystrophin were observed to be associated with both human and turkey (troponin T) and canine (dystrophin) dilated cardiomyopathies. This review gives an overview of the work carried out in cardiac troponin T and dystrophin to date in both human and animal dilated cardiomyopathy. |
| first_indexed | 2025-11-14T19:54:18Z |
| format | Article |
| id | nottingham-44092 |
| institution | University of Nottingham Malaysia Campus |
| institution_category | Local University |
| last_indexed | 2025-11-14T19:54:18Z |
| publishDate | 2017 |
| publisher | MDPI |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | nottingham-440922020-05-04T18:54:18Z https://eprints.nottingham.ac.uk/44092/ Multiple species comparison of cardiac troponin T and dystrophin: unravelling the DNA behind dilated cardiomyopathy England, Jennifer Loughna, Siobhan Rutland, Catrin S. Animals have frequently been used as models for human disorders and mutations. Following advances in genetic testing and treatment options, and the decreasing cost of these technologies in the clinic, mutations in both companion and commercial animals are now being investigated. A recent review highlighted the genes associated with both human and non-human dilated cardiomyopathy. Cardiac troponin T and dystrophin were observed to be associated with both human and turkey (troponin T) and canine (dystrophin) dilated cardiomyopathies. This review gives an overview of the work carried out in cardiac troponin T and dystrophin to date in both human and animal dilated cardiomyopathy. MDPI 2017-07-07 Article PeerReviewed England, Jennifer, Loughna, Siobhan and Rutland, Catrin S. (2017) Multiple species comparison of cardiac troponin T and dystrophin: unravelling the DNA behind dilated cardiomyopathy. Journal of Cardiovascular Development and Disease, 4 (3). 8/1-8/16. ISSN 2308-3425 Dilated cardiomyopathy; Troponin; Dystrophin; Mutation; Species https://doi.org/10.3390/jcdd4030008 doi:10.3390/jcdd4030008 doi:10.3390/jcdd4030008 |
| spellingShingle | Dilated cardiomyopathy; Troponin; Dystrophin; Mutation; Species England, Jennifer Loughna, Siobhan Rutland, Catrin S. Multiple species comparison of cardiac troponin T and dystrophin: unravelling the DNA behind dilated cardiomyopathy |
| title | Multiple species comparison of cardiac troponin T and dystrophin: unravelling the DNA behind dilated cardiomyopathy |
| title_full | Multiple species comparison of cardiac troponin T and dystrophin: unravelling the DNA behind dilated cardiomyopathy |
| title_fullStr | Multiple species comparison of cardiac troponin T and dystrophin: unravelling the DNA behind dilated cardiomyopathy |
| title_full_unstemmed | Multiple species comparison of cardiac troponin T and dystrophin: unravelling the DNA behind dilated cardiomyopathy |
| title_short | Multiple species comparison of cardiac troponin T and dystrophin: unravelling the DNA behind dilated cardiomyopathy |
| title_sort | multiple species comparison of cardiac troponin t and dystrophin: unravelling the dna behind dilated cardiomyopathy |
| topic | Dilated cardiomyopathy; Troponin; Dystrophin; Mutation; Species |
| url | https://eprints.nottingham.ac.uk/44092/ https://eprints.nottingham.ac.uk/44092/ https://eprints.nottingham.ac.uk/44092/ |