Comparative virus replication and host innate responses in human cells infected with three prevalent clades (2.3.4, 2.3.2, and 7) of highly pathogenic avian influenza H5N1 viruses
Highly pathogenic avian influenza H5N1 virus clades 2.3.4, 2.3.2, and 7 are the dominant cocirculating H5N1 viruses in poultry in China. However, humans appear to be clinically susceptible mostly to the 2.3.4 virus clade. Here, we demonstrated that A549 cells and human macrophages infected with clad...
| Main Authors: | Sun, H., Sun, Y., Pu, J., Zhang, Y., Zhu, Q., Li, J., Gu, J., Chang, K.-C., Liu, J. |
|---|---|
| Format: | Article |
| Published: |
American Society for Microbiology
2014
|
| Online Access: | https://eprints.nottingham.ac.uk/43921/ |
Similar Items
Continuing progress towards a unified nomenclature for the highly pathogenic H5N1 avian influenza viruses: Divergence of clade 2·2 viruses
by: Donis, R., et al.
Published: (2009)
by: Donis, R., et al.
Published: (2009)
Determination of avian influenza virus H5N2 infection in chicken innate immune cells
by: Mohd Zaini, Farhana, et al.
Published: (2013)
by: Mohd Zaini, Farhana, et al.
Published: (2013)
Prevailing PA mutation K356R in avian influenza H9N2 virus increases mammalian replication and pathogenicity
by: Xu, Guanlong, et al.
Published: (2016)
by: Xu, Guanlong, et al.
Published: (2016)
PA-X is a virulence factor in avian H9N2 influenza virus
by: Gao, Huijie, et al.
Published: (2015)
by: Gao, Huijie, et al.
Published: (2015)
Investigation of host innate antiviral mechanisms that block replication of influenza A virus and coronaviruses
by: Al-Beltagi, Sarah El-Sayed Abd El-Wahab
Published: (2025)
by: Al-Beltagi, Sarah El-Sayed Abd El-Wahab
Published: (2025)
Detection of avian influenza virus.
by: Omar, Abdul Rahman, et al.
Published: (2006)
by: Omar, Abdul Rahman, et al.
Published: (2006)
M gene reassortment in H9N2 influenza virus promotes early infection and replication: contribution to rising virus prevalence in chickens in China
by: Pu, Juan, et al.
Published: (2017)
by: Pu, Juan, et al.
Published: (2017)
Early apoptosis of porcine alveolar macrophages limits avian
influenza virus replication and proinflammatory dysregulation
by: Chang, Pengxiang, et al.
Published: (2015)
by: Chang, Pengxiang, et al.
Published: (2015)
Mammalian innate resistance to highly pathogenic avian influenza H5N1 virus infection is mediated through reduced proinflammation and infectious virus release
by: Nelli, Rahul K., et al.
Published: (2012)
by: Nelli, Rahul K., et al.
Published: (2012)
A novel antiviral peptide against avian influenza virus H9N2.
by: Yusoff, Khatijah, et al.
Published: (2008)
by: Yusoff, Khatijah, et al.
Published: (2008)
Detection of avian influenza A virus in Malaysian birds
by: Rahim, Z.A, et al.
Published: (2015)
by: Rahim, Z.A, et al.
Published: (2015)
Calcium dependent host innate immune resistance to influenza A virus infection
by: Goulding, Leah V.
Published: (2019)
by: Goulding, Leah V.
Published: (2019)
In Vitro And In Vivo Studies Of Malaysian Isolates Of Avian Influenza Virus
by: Ibrahim, Harith Mohammad
Published: (1993)
by: Ibrahim, Harith Mohammad
Published: (1993)
Bat lung epithelial cells show greater host species-specific innate resistance than MDCK cells to human and avian influenza viruses
by: Slater, Tessa, et al.
Published: (2018)
by: Slater, Tessa, et al.
Published: (2018)
Analysis of the interaction of influenza A virus with the PI3K pathway in different avian hosts
by: Di Lauro, Irene
Published: (2019)
by: Di Lauro, Irene
Published: (2019)
Epidemiology Of Influenza A Viruses In The Avian And Swine Populations In Peninsular Malaysia
by: Ramiah, Suriya Kumari
Published: (2008)
by: Ramiah, Suriya Kumari
Published: (2008)
Influenza A virus acquires enhanced pathogenicity and transmissibility after serial passages in swine
by: Wei, K., et al.
Published: (2014)
by: Wei, K., et al.
Published: (2014)
Identification and characterisation of a novel anti-viral peptide against avian influenza virus H9N2
by: Rajik, Mohamed, et al.
Published: (2009)
by: Rajik, Mohamed, et al.
Published: (2009)
Identification And Characterization Of A Novel Anti-Viral Peptide Against Avian Influenza Virus H9n2
by: Rajik, Mohamed
Published: (2009)
by: Rajik, Mohamed
Published: (2009)
Sequence analysis of the Malaysian low pathogenic avian influenza virus strain H5N2 from duck
by: Ahmad Rizal, Fatin, et al.
Published: (2023)
by: Ahmad Rizal, Fatin, et al.
Published: (2023)
Twenty amino acids at the C-terminus of PA-X are associated with increased influenza A virus replication and pathogenicity
by: Gao, Huijie, et al.
Published: (2015)
by: Gao, Huijie, et al.
Published: (2015)
Significant replication time-points of avian influenza A virus strain H5N1 in
Madin-Darby Canine Kidney cells
by: Toong, Seng Tan, et al.
Published: (2016)
by: Toong, Seng Tan, et al.
Published: (2016)
Genome characterisation and pathogenicity study of low pathogenic avian influenza virus subtype H9N2 isolated in Malaysia
by: Gunasekara, Erandi Maheshika
Published: (2022)
by: Gunasekara, Erandi Maheshika
Published: (2022)
Production, characterization and scaling up of monoclonal antibodies against neuraminidase glycoprotein of avian influenza virus subtype H9N2
by: Abdelaziz Fadul, Sana Awad
Published: (2011)
by: Abdelaziz Fadul, Sana Awad
Published: (2011)
Phylogenetic analysis of haemaglutinin gene of avian influenza virus isolate VRI1803/04
by: Zulkifli, Hazalina, et al.
Published: (2013)
by: Zulkifli, Hazalina, et al.
Published: (2013)
Virus-like particle vaccines: a prospective panacea against an avian influenza panzootic
by: Ninyio, Nathaniel Nyakaat, et al.
Published: (2020)
by: Ninyio, Nathaniel Nyakaat, et al.
Published: (2020)
Innate and adaptive immune evasion by dengue virus
by: Lee, Michelle Felicia *, et al.
Published: (2022)
by: Lee, Michelle Felicia *, et al.
Published: (2022)
Toward a unified nomenclature system for highly pathogenic avian influenza virus (H5N1)
by: Donis, R., et al.
Published: (2008)
by: Donis, R., et al.
Published: (2008)
Broadly cross-reactive immune responses in chickens immunized with chimeric virus-like particles of nodavirus displaying the M2e originated from avian and human influenza A viruses
by: Thian, Bernard Yi Zhe, et al.
Published: (2025)
by: Thian, Bernard Yi Zhe, et al.
Published: (2025)
Naturally occurring mutations in the PA gene are key contributors to increased virulence of pandemic H1N1/09 influenza virus in mice
by: Sun, Y., et al.
Published: (2014)
by: Sun, Y., et al.
Published: (2014)
Identification of morphological differences between avian influenza A viruses grown in chicken and duck cells
by: Al-Mubarak, Firas, et al.
Published: (2015)
by: Al-Mubarak, Firas, et al.
Published: (2015)
Enhanced pathogenicity and neurotropism of mouse-adapted H10N7 influenza virus are mediated by novel PB2 and NA mutations
by: Zhang, Xuxiao, et al.
Published: (2017)
by: Zhang, Xuxiao, et al.
Published: (2017)
Replication of a Malaysian Strain Avian Influenza A Virus H5N1 in Madin-Darby Canine Kidney and African Green Monkey Kidney cells
by: Tan, Toong Seng, et al.
Published: (2016)
by: Tan, Toong Seng, et al.
Published: (2016)
A novel peptide inhibits the influenza virus replication by preventing the viral attachment to the host cells.
by: Rajik, Mohamed, et al.
Published: (2009)
by: Rajik, Mohamed, et al.
Published: (2009)
The contribution of PA-X to the virulence of pandemic 2009 H1N1 and highly pathogenic H5N1 avian influenza viruses
by: Gao, Huijie, et al.
Published: (2015)
by: Gao, Huijie, et al.
Published: (2015)
Cellular transcripts regulated during infectinos with highly pathogenic H5N1 avian influenza virus in 3 host systems.
by: Balasubramanian, Vinod R.M.T, et al.
Published: (2011)
by: Balasubramanian, Vinod R.M.T, et al.
Published: (2011)
Morphological differences between avian influenza viruses grown in chicken and duck cells, a comparative study
by: Al-Mubarak, Firas
Published: (2014)
by: Al-Mubarak, Firas
Published: (2014)
Bat lung epithelial cells show variable species-specific susceptibility to human and avian influenza viruses
by: Slater, Tessa
Published: (2018)
by: Slater, Tessa
Published: (2018)
Cloning and expression of highly pathogenic avian influenza virus full-length nonstructural gene in Pichia pastoris.
by: M.B., Abu Bakar, et al.
Published: (2011)
by: M.B., Abu Bakar, et al.
Published: (2011)
Highly pathogenic avian influenza virus nucleoprotein interacts with TREX complex adaptor protein Aly/REF
by: Balasubramaniam, Vinod R. M. T., et al.
Published: (2013)
by: Balasubramaniam, Vinod R. M. T., et al.
Published: (2013)
Similar Items
-
Continuing progress towards a unified nomenclature for the highly pathogenic H5N1 avian influenza viruses: Divergence of clade 2·2 viruses
by: Donis, R., et al.
Published: (2009) -
Determination of avian influenza virus H5N2 infection in chicken innate immune cells
by: Mohd Zaini, Farhana, et al.
Published: (2013) -
Prevailing PA mutation K356R in avian influenza H9N2 virus increases mammalian replication and pathogenicity
by: Xu, Guanlong, et al.
Published: (2016) -
PA-X is a virulence factor in avian H9N2 influenza virus
by: Gao, Huijie, et al.
Published: (2015) -
Investigation of host innate antiviral mechanisms that block replication of influenza A virus and coronaviruses
by: Al-Beltagi, Sarah El-Sayed Abd El-Wahab
Published: (2025)