A single dose of cannabidiol reduces blood pressure in healthy volunteers in a randomized crossover study

QR Code

A single dose of cannabidiol reduces blood pressure in healthy volunteers in a randomized crossover study

BACKGROUND. Cannabidiol (CBD) is a nonpsychoactive phytocannabinoid used in multiple sclerosis and intractable epilepsies. Preclinical studies show CBD has numerous cardiovascular benefits, including a reduced blood pressure (BP) response to stress. The aim of this study was to investigate if CBD re...

Full description

Bibliographic Details
Main Authors:	Jadoon, Khalid A., Tan, Garry D., O'Sullivan, Saoirse
Format:	Article
Published:	American Society for Clinical Investigation 2017
Online Access:	https://eprints.nottingham.ac.uk/43903/

Similar Items

In vivo cannabidiol treatment improves endothelium-dependent vasorelaxation in mesenteric arteries of Zucker diabetic fatty rats
by: Wheal, Amanda J., et al.
Published: (2017)

Efficacy and safety of Cannabidiol and Tetrahydrocannabivarin on glycemic and lipid parameters in patients with Type 2 diabetes: a randomized, double-blind, placebo-controlled, parallel group pilot study
by: Jadoon, Khalid A., et al.
Published: (2016)

A systematic review and meta-analysis of the haemodynamic effects of cannabidiol
by: Sultan, Salahaden R., et al.
Published: (2017)

Cannabidiol and palmitoylethanolamide are anti-inflammatory in the acutely inflamed human colon
by: Couch, Daniel G., et al.
Published: (2017)

Effects of a nitrate-rich meal on arterial stiffness and blood pressure in healthy volunteers
by: Liu, A., et al.
Published: (2013)

Nitrate-rich vegetables do not lower blood pressure in individuals with mildly elevated blood pressure: A 4-wk randomized controlled crossover trial
by: Blekkenhorst, L., et al.
Published: (2018)

Cardioprotective effects of yellowstripe scad compared to salmon among healthy overweight adults in a randomized crossover trial
by: Chang, Wei Lin
Published: (2019)

Subcutaneous administration of benzathine benzylpenicillin G has favourable pharmacokinetic characteristics for the prevention of rheumatic heart disease compared with intramuscular injection: A randomized, crossover, population pharmacokinetic study in healthy adult volunteers
by: Kado, J.H., et al.
Published: (2020)

Investigation of selected foods added with fenugreek that controls postprandial blood glucose in healthy volunteers
by: Robert, Sathyasurya Daniel
Published: (2018)

Effect of various doses of cinnamon on blood glucose in diabetic individuals
by: Jadoon, Mahpara Safdar, et al.
Published: (2004)

THE ACUTE EFFECTS OF QUERCETIN-3-O-GLUCOSIDE ON ENDOTHELIAL FUNCTION AND BLOOD PRESSURE: A RANDOMIZED DOSE-RESPONSE STUDY
by: Bondonno, N., et al.
Published: (2017)

Acute effects of quercetin-3-O-glucoside on endothelial function and blood pressure: a randomized dose-response study
by: Bondonno, N., et al.
Published: (2016)

Efficacy and Safety of Quarter-Dose Blood Pressure-Lowering Agents: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
by: Bennett, A., et al.
Published: (2017)

Cannabidiol regulation of extinction and relapse of learned fear
by: Papagianni, Eleni
Published: (2023)

The actions of cannabidiol and palmitoylethanolamide on inflammation and permeability of the gut
by: Couch, Daniel
Published: (2018)

Bidirectional effects of cannabidiol on contextual fear memory extinction
by: Song, Chenchen, et al.
Published: (2016)

The effects of blood pressure reduction and of different blood pressure-lowering regimens on major cardiovascular events according to baseline blood pressure: Meta-analysis of randomized trials
by: Czernichow, S., et al.
Published: (2011)

Oesophageal Doppler guided optimization of cardiac output does not increase visceral microvascular blood flow in healthy volunteers
by: Heinink, Thomas P., et al.
Published: (2017)

Reliability of pressure pain threshold testing in healthy pain free young adults
by: Waller, R., et al.
Published: (2015)

Acute effects of chlorogenic acids on endothelial function and blood pressure in healthy men and women
by: Ward, Natalie, et al.
Published: (2016)

Cannabidiol regulation of learned fear: implications for treating anxiety-related disorders
by: Jurkus, Regimantas, et al.
Published: (2016)

Dexamphetamine effects on prepulse inhibition (PPI) and startle in healthy volunteers
by: Chitty, K., et al.
Published: (2014)

A new real coded genetic algorithm crossover: Rayleigh crossover
by: Lim, Siew Mooi, et al.
Published: (2014)

Analysis of peripheral blood of ovarian cancer patients indicates higher sub-populations of natural killer and B cells compared to healthy volunteers
by: Tan, Jun Hao, et al.
Published: (2014)

Characterisation of the haemodynamic effects of cannabidiol in humans using duplex ultrasound and other techniques
by: Sultan, Salahaden
Published: (2020)

Learned fear extinction: an interdisciplinary investigation of the neurocircuitry and the potential therapeutic benefit of cannabidiol
by: Jurkus, Regimantas
Published: (2019)

The effect of hearing augmentation on cognitive assessment scores: a pilot crossover randomized controlled trial
by: Ibrahim, Amirah Fatin, et al.
Published: (2016)

Dietary fructose in relation to blood pressure and serum uric acid in adolescent boys and girls
by: Bobridge, K., et al.
Published: (2013)

The impact of step count reduction and remobilisation on body composition, blood glucose disposal and muscle protein turnover in healthy, active young and older volunteers
by: Creedon, Lee
Published: (2025)

Quarter-dose quadruple combination therapy for initial treatment of hypertension: placebo-controlled, crossover, randomised trial and systematic review
by: Chow, C., et al.
Published: (2017)

High-dose intravenous epoetin does not increase blood pressure in critically ill patients with acute kidney injury
by: Md Ralib, Azrina
Published: (2013)

Development and evaluation of cannabidiol formulations for delivery to the central nervous system to treat neuropathic pain
by: Muresan, Paula Diana
Published: (2022)

Effect of adding milk to black tea on vascular function in healthy men and women: a randomised controlled crossover trial
by: Ahmad, A., et al.
Published: (2018)

Dietary manipulation of brown adipose tissue (BAT) thermogenesis in healthy adult volunteers
by: Vazquez Rocha, Lucia del Carmen
Published: (2019)

Dynamic assessment of the electrocardiographic QT interval during citrate infusion in healthy Volunteers
by: Davis, T.M.E, et al.
Published: (1995)

Endocannabinoids modulate human blood-brain barrier permeabilityin vitro
by: Hind, William H., et al.
Published: (2015)

Acute high-dose intravenous epoetin did not increase blood pressure in critically ill patients with acute kidney injury
by: Endre, Zoltan H., et al.
Published: (2011)

Fasting and glucose induced thermogenesis in response to three ambient temperatures: a randomized crossover trial in the metabolic syndrome
by: Pathak, Kaveri, et al.
Published: (2018)

Response-order effects in survey methods: A randomized controlled crossover study in the context of sport injury prevention
by: Chan, Derwin, et al.
Published: (2015)

Self-assembling multi-layer Pd nanoparticles onto Nafion(TM) membrane to reduce methanol crossover
by: Tang, H., et al.
Published: (2005)