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Novel hybrids of natural β-elemene bearing isopropanolamine moieties: synthesis, enhanced anticancer profile, and improved aqueous solubility

A series of novel β-elemene isopropanolamine derivatives were synthesized and evaluated for their antitumor activity. The results indicated that all of the compounds showed stronger antiproliferative activities than β-elemene as well as improved aqueous solubility. In particular dimer 6q showed the...

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Bibliographic Details
Main Authors:	Chen, Jichao, Wang, Tianyu, Xu, Shengtao, Aijun, Lin, Yao, Hequan, Xie, Weijia, Zhu, Zheying, Xu, Jinyi
Format:	Article
Published:	Elsevier 2017
Subjects:	β-Elemene; Isopropanolamine; Dimer; Antitumor activity; Aqueous solubility
Online Access:	https://eprints.nottingham.ac.uk/43894/

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