A practical and catalyst-free trifluoroethylation reaction of amines using trifluoroacetic acid

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A practical and catalyst-free trifluoroethylation reaction of amines using trifluoroacetic acid

Amines are a fundamentally important class of biologically active compounds and the ability to manipulate their physicochemical properties through the introduction of fluorine is of paramount importance in medicinal chemistry. Current synthesis methods for the construction of fluorinated amines rely...

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Bibliographic Details
Main Authors:	Andrews, Keith G., Faizova, Radmilla, Denton, Ross M.
Format:	Article
Published:	Nature Publishing Group 2017
Online Access:	https://eprints.nottingham.ac.uk/43664/

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