The novel roles of DNA damage repair proteins ATM and DNA-PK in the regulation of the ER stress response and IL-23 expression in dendritic cells
Dendritic cells (DC) are the principal, cross-priming antigen-presenting cell responsible for naïve T cell activation and differentiation. Specific programmes of cytokine secretion by DC are particularly important for the polarisation of CD4+ T-cells to discrete effector populations i.e. Th1, Th17,...
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| Format: | Thesis (University of Nottingham only) |
| Language: | English |
| Published: |
2017
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| Subjects: | |
| Online Access: | https://eprints.nottingham.ac.uk/43550/ |
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