Enantioselective copper-catalyzed reductive coupling of vinylazaarenes with N-Boc aldimines

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Enantioselective copper-catalyzed reductive coupling of vinylazaarenes with N-Boc aldimines

The diastereo- and enantioselective reductive coupling of vinylazaarenes with N-Boc aldimines is described. The reactions proceed using chiral copper–bisphosphine complexes in the presence of TMDS as a hydride source to give reductive coupling products in moderate to high enantioselectivities.

Bibliographic Details
Main Authors:	Choi, Bonnie, Saxena, Aakarsh, Smith, Joshua J., Churchill, Gwydion H., Lam, Hon Wai
Format:	Article
Published:	Thieme 2015
Subjects:	Asymmetric catalysis Copper Enantioselectivity Imines Vinylazaarenes
Online Access:	https://eprints.nottingham.ac.uk/43480/

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