Enantioselective copper-catalyzed reductive coupling of vinylazaarenes with N-Boc aldimines
The diastereo- and enantioselective reductive coupling of vinylazaarenes with N-Boc aldimines is described. The reactions proceed using chiral copper–bisphosphine complexes in the presence of TMDS as a hydride source to give reductive coupling products in moderate to high enantioselectivities.
| Main Authors: | , , , , |
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| Format: | Article |
| Published: |
Thieme
2015
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| Subjects: | |
| Online Access: | https://eprints.nottingham.ac.uk/43480/ |
| Summary: | The diastereo- and enantioselective reductive coupling of vinylazaarenes with N-Boc aldimines is described. The reactions proceed using chiral copper–bisphosphine complexes in the presence of TMDS as a hydride source to give reductive coupling products in moderate to high enantioselectivities. |
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