Translational control of epidermal growth factor receptor in neurodegenerative diseases

QR Code

Translational control of epidermal growth factor receptor in neurodegenerative diseases

Epidermal growth factor receptor (EGFR) is a key modulator of a number of cellular processes such as cell fate, proliferation, migration, and apoptosis. The EGFR gene is commonly amplified in a number of cancers and EGFR has been implicated in Alzheimer’s disease, but its role in this context is unc...

Full description

Bibliographic Details
Main Author:	Smalley, Daniel. S.
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2017
Subjects:	epidermal growth factor receptor EGFR translational regulation Alzheimer’s disease
Online Access:	https://eprints.nottingham.ac.uk/43474/

Similar Items

Biological significance of human epidermal growth factor receptor 2 (HER2) in breast cancer: effect of oestrogen receptor
by: Ahmad, Dena Akram Jerjees
Published: (2016)

Translational control of Human Epidermal Growth Factor Receptors, HER2 and HER4 in response to cellular stresses in breast cancer cells
by: Edwards, Arnelle
Published: (2023)

Healing properties of epidermal growth factor and tocotrienol-rich fraction formulation in deep partial-thickness burn wound model
by: Guo, Hui-Fang
Published: (2017)

Expression of human epidermal growth factor in pichia pastoris and optimization of fermentation conditions
by: Eissazadeh, Samira
Published: (2012)

Recovery and purification of epidermal growth factor from fermentation broth using expanded bed chromatography
by: Rosti, Ira Amira
Published: (2013)

Simple surface plasmon resonance bio-sensor for the quantification of recombinant human epidermal growth factor (rhEGF) in expanded bed recovery
by: Faizal Wong, Fadzlie Wong
Published: (2010)

Understanding the role of eIF4A in gene regulation in health and disease
by: Webb, Thomas E.
Published: (2012)

Exploring block and permeation of N-methyl-D-Aspartate (NMDA) receptor channels for treatment of neurodegenerative disorders
by: Abu, Izuddin Fahmy
Published: (2016)

The effect of memantine and the ladybird alkaloid, harmonine, on NMDA receptor function and Alzheimer’s disease
by: Kaur, Kiran
Published: (2022)

Sulfated galactans from red seaweed Gracilaria fisheri target epidermal growth factor receptor (EGFR) and inhibit cholangiocarcinoma cells (CCA) proliferation
by: Sae-lao, Thannich, et al.
Published: (2017)

Molecular genetic studies in pregnancies affected by preeclampsia and intrauterine growth restriction
by: Abd-Rabou, Ayat Abdel-Rahman Sayed
Published: (2011)

Investigation into patterns of epigenetic regulation of Alzheimer’s disease
by: Boden, Kirsty
Published: (2019)

Glycosylated notch and cancer
by: Pakkiriswami, Shanmugasundaram, et al.
Published: (2016)

Investigating polygenic risk scores in Alzheimer's disease
by: Chaudhury, Sultan Raja
Published: (2024)

Latrepirdine: Molecular mechanisms underlying potential therapeutic roles in Alzheimer’s and other neurodegenerative diseases
by: Bharadwaj, P., et al.
Published: (2013)

Recent progress in translational research on neurovascular and neurodegenerative disorders
by: Demuth, Hans-Ulrich, et al.
Published: (2017)

Sulfated galactans from the red seaweed Gracilaria fisheri exerts anti-migration effect on cholangiocarcinoma cells
by: Sae-Lao, Thannicha, et al.
Published: (2017)

Effects of postbiotic and inulin supplements on growth performance, gut morphology, gene expression and fecal characteristics of broiler chicken
by: Karrem, Karwan Yaseen
Published: (2016)

Supplementation of postbiotic RG14 in post-weaning dorper lambs to enhance growth performance, gut health and immunity
by: Wan Ibrahim, Wan Ahmad Izuddin
Published: (2018)

Ontogeny and nutritional programming of the hepatic growth hormone-insulin-like growth factor-prolactin axis in the sheep
by: Hyatt, M.A., et al.
Published: (2007)

Understanding haemodynamics in neurodegenerative disease
by: Dury, R.J.
Published: (2018)

Alzheimer's beta-amyloid peptides compete for insulin binding to the insulin receptor
by: Xie, Ling, et al.
Published: (2002)

Development of an allele-specific polymerase chain reaction genotyping test and association of selected single nucleotide polymorphisms and analytes with the risk of alzheimer’s disease / Mohd Nazif Samat @ Darawi
by: Samat @ Darawi, Mohd Nazif
Published: (2014)

Dynamics of ligand and nanobody binding at CXCR4/EGFR complexes
by: Comez, Dehan
Published: (2025)

Default mode network perturbations in Alzheimer's disease: an fMRI study in Klang Valley, Malaysia
by: Mohad Azmi, Nur Hafizah, et al.
Published: (2024)

A histological and micro-CT investigation in to the effect of NGF and EGF on the periodontal, alveolar bone, root and pulpal healing of replanted molars in a rat model - a pilot study
by: Furfaro, F., et al.
Published: (2014)

Investigating genetic variation in Alzheimer’s disease
by: Patel, Tulsi
Published: (2018)

Multitarget drug design strategy in Alzheimer’s disease: focus on cholinergic transmission and amyloid-β aggregation
by: Simioni, Elena, et al.
Published: (2017)

Cellular acidification as a new approach to cancer treatment and to the understanding and therapeutics of neurodegenerative diseases
by: Harguindey, Salvador, et al.
Published: (2017)

An evaluation of DREADD receptor pharmacology in recombinant cells and astrocytes
by: Carpenter, Jessica
Published: (2020)

Investigating Molecular Interactions of Thyroid Hormone and Androgen Receptors
by: Zhao, Yi
Published: (2023)

Neuroprotective effects of thymoquinone-rich fraction and thymoquinone nanoemulsions in sporadic alzheimer’s disease rat model
by: Ismail, Norsharina
Published: (2019)

Translation shifts in aljazeera and BBC translations of obama’s speech on the Arab spring
by: Tawfiq, Nazar Mohammed
Published: (2019)

Medicinal Chemistry & Chemical Biology Approaches to Investigate Prospective Treatments for CNS Diseases: Dopamine D1 Receptor Positive Allosteric Modulators, Dopamine D2 Receptor Positive & Negative Allosteric Modulators, Dopamine D2 Receptor-Ligand Kinetics
by: Fyfe, Tim
Published: (2019)

Rationalising the role of Keratin 9 as a biomarker for Alzheimer’s disease
by: Richens, Joanna L., et al.
Published: (2016)

Assessment of the molecular mechanisms of action of novel 4-phenylpyridine-2-one and 6-phenylpyrimidin-4-one allosteric modulators at the M1 muscarinic acetylcholine receptors
by: van der Westhuizen, Emma T., et al.
Published: (2018)

Gender on translation evaluation in Malaysia
by: S., Vijayaletchumy
Published: (2011)

Prediction of Alzheimer disease using improved MMSE ensemble regressor based on magnetic resonance images
by: Farzan, Ali
Published: (2015)

Consumption of fish and Alzheimer's Disease
by: Newton, Wendy, et al.
Published: (2011)

Making the ‘Invisible’ Visible?: Reviews of Translated Works in the United Kingdom, France and Germany
by: Gray, Martyn P
Published: (2021)