Multicomponent analysis of the tumour microenvironment reveals low CD8 T cell number, low stromal caveolin-1 and high tenascin-C and their combination as significant prognostic markers in non-small cell lung cancer

Multicomponent analysis of the tumour microenvironment reveals low CD8 T cell number, low stromal caveolin-1 and high tenascin-C and their combination as significant prognostic markers in non-small cell lung cancer

The complex interplay of the tumour microenvironment (TME) and its role in disease progression and response to therapy is poorly understood. The majority of studies to date focus on individual components or molecules within the TME and so lack the power correlative analysis. Here we have performed a...

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Bibliographic Details
Main Authors: Onion, David, Isherwood, Mark, Shridhar, Naveen, Xenophontos, Mikalena, Craze, Madeleine L., Day, Laura J., Gárcia-Marquez, Maria A., Pineda, Robert G., Reece-Smith, Alex M., Saunders, John H., Duffy, John P., Argent, Richard H., Grabowska, Anna M.
Format: Article
Published: Impact Journals 2017
Subjects:
Non-Small Cell Lung Cancer
Tumour microenvironment
Caveolin-1
Tenascin-C
T Cell
Online Access:https://eprints.nottingham.ac.uk/43438/

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