Enhanced expression of Organic Cation Transporters in bronchial epithelial cell layers following insults associated with asthma – impact on salbutamol transport

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Enhanced expression of Organic Cation Transporters in bronchial epithelial cell layers following insults associated with asthma – impact on salbutamol transport

Increasing evidence suggests Organic Cation Transporters (OCT) might facilitate the absorption of inhaled bronchodilators, including salbutamol, across the lung epithelium. This is essentially scarred and inflamed in asthma. Accordingly, the impact of epithelial insults relevant to asthma on OCT exp...

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Bibliographic Details
Main Authors:	Mukherjee, Manali, Cingolani, Emanuela, Pritchard, D.I., Bosquillon, Cynthia
Format:	Article
Published:	Elsevier 2017
Subjects:	Airway epithelium; Drug transporters; Permeability; Inflammation; In vitro model
Online Access:	https://eprints.nottingham.ac.uk/43428/

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