Controlled release of GAG-binding enhanced transduction (GET) peptides for sustained and highly efficient intracellular delivery
Controlled release systems for therapeutic molecules are vital to allow the sustained local delivery of their activities which direct cell behaviour and enable novel regenerative strategies. Direct programming of cells using exogenously delivered transcription factors can by-pass growth factor signa...
| Main Authors: | Abu-Awwad, Hosam Al-Deen M., Thiagarajan, Lalitha, Dixon, James E. |
|---|---|
| Format: | Article |
| Published: |
Elsevier
2017
|
| Subjects: | |
| Online Access: | https://eprints.nottingham.ac.uk/43423/ |
Similar Items
Highly efficient intracellular transduction in three-dimensional gradients for programming cell fate
by: Eltaher, Hoda M., et al.
Published: (2016)
by: Eltaher, Hoda M., et al.
Published: (2016)
Osteogenic programming of human mesenchymal stem cells with highly efficient intracellular delivery of RUNX2
by: Thiagarajan, Lalitha, et al.
Published: (2017)
by: Thiagarajan, Lalitha, et al.
Published: (2017)
PEGylated enhanced cell penetrating peptide nanoparticles for lung gene therapy
by: Osman, Gizem, et al.
Published: (2018)
by: Osman, Gizem, et al.
Published: (2018)
Suppression of essential pro-inflammatory signaling pathways by natural agents for the therapy of Multiple Myeloma
by: Sikka, S., et al.
Published: (2014)
by: Sikka, S., et al.
Published: (2014)
The effect of hypoxia and reoxygenation on STAT3 regulation in potential cardiomyocyte models
by: Evans, Emma Louise
Published: (2012)
by: Evans, Emma Louise
Published: (2012)
Quantitative proteomic analysis of G-protein signallingin Stagonospora nodorum using isobaric tags forrelative and absolute quantification
by: Casey, T., et al.
Published: (2010)
by: Casey, T., et al.
Published: (2010)
Differentiation of embryonic stem cells through controlled release of growth factors from microspheres
by: olaye, eghosa omoregie andrew/ E A O
Published: (2009)
by: olaye, eghosa omoregie andrew/ E A O
Published: (2009)
In vivo evaluation of different formulation strategies for sustained release injectables of a poorly soluble HIV protease inhibitor
by: Muees, Joke, et al.
Published: (2015)
by: Muees, Joke, et al.
Published: (2015)
Proteomic identification of extracellular proteins regulated by the Gna1 Gα subunit in Stagonospora nodorum
by: Tan, Kar-Chun, et al.
Published: (2009)
by: Tan, Kar-Chun, et al.
Published: (2009)
Histidine146 of Human Serum Albumin Plays a Prominent Role at the Interface of Subdomains IA and IIA in Allosteric Ligand Binding
by: Kaneko, K., et al.
Published: (2011)
by: Kaneko, K., et al.
Published: (2011)
Design and development of injectable intraperitoneal sustained release drug delivery system for ovarian cancer
by: Nazir, Chaudhry Zahid
Published: (2020)
by: Nazir, Chaudhry Zahid
Published: (2020)
DEF6 aggregation is linked to active translation and mRNA turnover in T cells
by: Remon, Kerry
Published: (2017)
by: Remon, Kerry
Published: (2017)
Photochemical characterization of a novel fungal rhodopsin from Phaeosphaeria nodorum
by: Fan, Ying, et al.
Published: (2011)
by: Fan, Ying, et al.
Published: (2011)
Influence of fresh and thermoxidized carotino oil on Cyclic Guanosine Monophosphate (cGMP) in erythrocytes from Sprague dawley rats / Mohd Fakharul Zaman Raja Yahya and Athifah Najwani Shahidan
by: Raja Yahya, Mohd Fakharul Zaman, et al.
Published: (2012)
by: Raja Yahya, Mohd Fakharul Zaman, et al.
Published: (2012)
The Mak2 MAP kinase signal transduction pathway is required for pathogenicity in Stagonospora nodorum
by: Solomon, P., et al.
Published: (2005)
by: Solomon, P., et al.
Published: (2005)
DEF6, a novel substrate for the tec kinase ITK, contains a glutamine-rich aggregation-prone region and forms cytoplasmic granules that co-localize with P-bodies
by: Hey, Fiona, et al.
by: Hey, Fiona, et al.
Modulating oxytocin brain penetration via intranasal delivery and a novel conjugate peptide (OT-GET)
by: Wong, Sara Wei Ting
Published: (2022)
by: Wong, Sara Wei Ting
Published: (2022)
Ion pairing LC-MS/MS method for analysis of intracellular phosphorylated metabolites
by: Utami, Wahyu
Published: (2015)
by: Utami, Wahyu
Published: (2015)
Interaction of ARC and Daxx: a novel endogenous target to
preserve motor function and cell loss after focal brain
ischemia in mice
by: Donath, Stefan, et al.
Published: (2016)
by: Donath, Stefan, et al.
Published: (2016)
Emerging role of the KRAS-PDK1 axis in pancreatic cancer
by: Ferro, R., et al.
Published: (2014)
by: Ferro, R., et al.
Published: (2014)
Gradient delivery of bioactive molecules across porous hydrogels
by: Eltaher, Hoda M.M.A.
Published: (2016)
by: Eltaher, Hoda M.M.A.
Published: (2016)
Cordycepin affects growth factor-dependent gene expression
by: Lin, Jialiang
Published: (2018)
by: Lin, Jialiang
Published: (2018)
Effects of intracellular calcium ions in causing apoptosis of Hep-G2 liver cell lines after infection with Leptospira interrogans
by: Mohd Hafiz Ngoo, Muhamad Sofie
Published: (2018)
by: Mohd Hafiz Ngoo, Muhamad Sofie
Published: (2018)
(Dys)Regulation of Insulin Secretion by Macronutrients
by: Newsholme, Philip, et al.
Published: (2015)
by: Newsholme, Philip, et al.
Published: (2015)
Developing an Oral-Insulin-Delivery System using GET-peptide-mediated transcytosis
by: Rehmani, Sahrish
Published: (2021)
by: Rehmani, Sahrish
Published: (2021)
Controlled release system for delivery of GET peptide and its application for transcription factor delivery for bone regeneration
by: Abu Awwad, Hosam Al-Deen
Published: (2018)
by: Abu Awwad, Hosam Al-Deen
Published: (2018)
Porphyrinic-nanoplatforms: controlled intracellular generation of reactive oxygen species in human mesenchymal stem cells
by: Lavado, Andrea Sofia Caetano das Neves
Published: (2014)
by: Lavado, Andrea Sofia Caetano das Neves
Published: (2014)
Increases in intracellular calcium perturb blood–brain barrier via protein kinase C-alpha and apoptosis
by: Rakkar, Kamini, et al.
Published: (2016)
by: Rakkar, Kamini, et al.
Published: (2016)
Fast, ultrasensitive detection of reactive oxygen species using a carbon nanotube based-electrocatalytic intracellular sensor
by: Rawson, Frankie J., et al.
Published: (2015)
by: Rawson, Frankie J., et al.
Published: (2015)
Concise review: Reprogramming, behind the scenes: noncanonical neural stem cell signaling pathways reveal new, unseen regulators of tissue plasticity with therapeutic implications
by: Poser, Steven W., et al.
Published: (2015)
by: Poser, Steven W., et al.
Published: (2015)
Development of fluorescent nanosensors for real-time biological assays
by: Elsutohy, Mohamed
Published: (2016)
by: Elsutohy, Mohamed
Published: (2016)
Subcellular calcium patterns in ventricular myocytes
by: Veasy, Joshua
Published: (2018)
by: Veasy, Joshua
Published: (2018)
Carbene in cupredoxin protein scaffolds: replacement of a histidine ligand in the active site substantially alters copper redox properties
by: Planchestainer, Matteo, et al.
Published: (2018)
by: Planchestainer, Matteo, et al.
Published: (2018)
A combined theoretical and experimental study of the structure and vibrational adsorption, vibrational circular dichroism, Raman and Raman optical activity spectra of the L-histidine zwitterion
by: Deplazes, Evelyne, et al.
Published: (2007)
by: Deplazes, Evelyne, et al.
Published: (2007)
Molecular modelling of the interactions of complex carbohydrates with proteins
by: Gandhi, Neha Sureshchandra
Published: (2011)
by: Gandhi, Neha Sureshchandra
Published: (2011)
Halogen-substituted ureas for anion binding: solid state and solution studies
by: Casula, Arianna, et al.
Published: (2017)
by: Casula, Arianna, et al.
Published: (2017)
A biodegradable antibiotic-impregnated scaffold to prevent osteomyelitis in a contaminated in vivo bone defect model
by: McLaren, Jane S., et al.
Published: (2014)
by: McLaren, Jane S., et al.
Published: (2014)
A polymeric protein-loaded microsphere delivery system for use in bone tissue engineering
by: Boukari, Yamina
Published: (2017)
by: Boukari, Yamina
Published: (2017)
Hes3 is expressed in the adult pancreatic islet and regulates gene expression, cell growth, and insulin release
by: Masjkur, Jimmy, et al.
Published: (2014)
by: Masjkur, Jimmy, et al.
Published: (2014)
Stereoselective Binding of Human Serum Albumin
by: Chuang, Victor, et al.
Published: (2006)
by: Chuang, Victor, et al.
Published: (2006)
Similar Items
-
Highly efficient intracellular transduction in three-dimensional gradients for programming cell fate
by: Eltaher, Hoda M., et al.
Published: (2016) -
Osteogenic programming of human mesenchymal stem cells with highly efficient intracellular delivery of RUNX2
by: Thiagarajan, Lalitha, et al.
Published: (2017) -
PEGylated enhanced cell penetrating peptide nanoparticles for lung gene therapy
by: Osman, Gizem, et al.
Published: (2018) -
Suppression of essential pro-inflammatory signaling pathways by natural agents for the therapy of Multiple Myeloma
by: Sikka, S., et al.
Published: (2014) -
The effect of hypoxia and reoxygenation on STAT3 regulation in potential cardiomyocyte models
by: Evans, Emma Louise
Published: (2012)