Adverse effects of antipsychotics on micro-vascular endothelial cells of the human blood–brain barrier

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Adverse effects of antipsychotics on micro-vascular endothelial cells of the human blood–brain barrier

Although the mechanisms of action of antipsychotics (APs) on neuronal function are well understood, very little is known about their effects on cells of the blood–brain barrier (BBB); one function of which is to limit the access of these amphiphilic compounds to the central nervous system. To addres...

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Bibliographic Details
Main Authors:	Elmorsy, Ekramy, Elzalabany, Laila M., Elsheikha, Hany M., Smith, Paul A.
Format:	Article
Published:	Elsevier 2014
Subjects:	Antipsychotic; Blood–brain barrier; Apoptosis; Evans blue; Endothelium; ROS
Online Access:	https://eprints.nottingham.ac.uk/43321/

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