RORγt+ innate lymphoid cells promote lymph node metastasis of breast cancers

RORγt+ innate lymphoid cells promote lymph node metastasis of breast cancers

Cancer cells tend to metastasize first to tumor-draining lymph nodes, but the mechanisms mediating cancer cell invasion into the lymphatic vasculature remain little understood. Here, we show that in the human breast tumor microenvironment (TME), the presence of increased numbers of RORγt+ group 3 in...

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Bibliographic Details
Main Authors: Irshad, Sheeba, Flores-Borja, Fabian, Lawler, Katherine, Monypenny, James, Evans, Rachel, Male, Victoria, Gordon, Peter, Cheung, Anthony, Gazinska, Patrycja, Noor, Farzana, Wong, Felix, Grigoriadis, Anita, Fruhwirth, Gilbert O., Barber, Paul R., Woodman, Natalie, Martin, Stewart G.
Format: Article
Published: American Association for Cancer Research 2017
Online Access:https://eprints.nottingham.ac.uk/43055/

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