Sulfated galactans from red seaweed Gracilaria fisheri target epidermal growth factor receptor (EGFR) and inhibit cholangiocarcinoma cells (CCA) proliferation

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Sulfated galactans from red seaweed Gracilaria fisheri target epidermal growth factor receptor (EGFR) and inhibit cholangiocarcinoma cells (CCA) proliferation

Cholangiocarcinoma (CCA) is increasing in incidence worldwide and is resistant to chemotherapeutic agents, making treatment of CCA a major challenge. Previous studies reported that natural sulfated polysaccharides (SPs) disrupted growth factor receptor activation in cancer cells. The present study,...

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Bibliographic Details
Main Authors:	Sae-lao, Thannich, Tohtong, Rutaiwan, Bates, David O., Wongprasert, Kanokpan
Format:	Article
Published:	World Scientific Publishing 2017
Subjects:	Cholangiocarcinoma; EGFR; Gracilaria fisheri; Sulfated Galactans; AntiProliferation
Online Access:	https://eprints.nottingham.ac.uk/43028/

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