An internal ribosome entry site in the 5′ untranslated region of epidermal growth factor receptor allows hypoxic expression
The expression of epidermal growth factor receptor (EGFR/ERBB1/HER1) is implicated in the progress of numerous cancers, a feature that has been exploited in the development of EGFR antibodies and EGFR tyrosine kinase inhibitors as anti-cancer drugs. However, EGFR also has important normal cellular f...
| Main Authors: | , , , |
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| Format: | Article |
| Published: |
Nature Publishing Group
2015
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| Online Access: | https://eprints.nottingham.ac.uk/42877/ |