Cathepsin K in lymphangioleiomyomatosis: LAM cell-fibroblast Interactions enhance protease activity by extracellular acidification

QR Code

Cathepsin K in lymphangioleiomyomatosis: LAM cell-fibroblast Interactions enhance protease activity by extracellular acidification

Lymphangioleiomyomatosis (LAM) is a rare disease in which clonal ‘LAM’ cells infiltrate the lungs and lymphatics. In association with recruited fibroblasts, LAM cells form nodules adjacent to lung cysts. It is assumed LAM nodule derived proteases lead to cyst formation although, this is uncertain. W...

Full description

Bibliographic Details
Main Authors:	Dongre, Arundhati, Clements, Debbie, Fisher, Andrew J., Johnson, Simon R.
Format:	Article
Published:	Elsevier 2017
Online Access:	https://eprints.nottingham.ac.uk/42865/

Similar Items

Modelling lymphangioleiomyomatosis (LAM) using two-dimensional and three-dimensional in vitro co-culture systems
by: Dongre, Arundhati
Published: (2018)

Crystallographic and docking (Cathepsins B, K, L and S) studies on bioactive halotelluroxetanes
by: Caracelli, Ignez, et al.
Published: (2018)

Extracellular matrix glycoproteins of skin fibroblasts in tuberous sclerosis
by: Uysal, Hamdi
Published: (1995)

Dermal fibroblast extracellular matrix regulates keratinocyte behaviour
by: Wong, Chee Wai
Published: (2017)

Production of extracellular protease enzyme by aspergillus niger
by: Siti Khairunnisa, Daud
Published: (2012)

The vitamin D binding protein axis modifies disease severity in Lymphangioleiomyomatosis
by: Miller, Suzanne, et al.
Published: (2018)

A 2-year randomised placebo-controlled trial of doxycycline for lymphangioleiomyomatosis
by: Chang, William Y.C., et al.
Published: (2014)

Twin pregnancy following sirolimus therapy in lymphangioleiomyomatosis
by: Andrea YLB,, et al.
Published: (2022)

Lung function response and side effects to rapamycin for lymphangioleiomyomatosis: a prospective national cohort study
by: Bee, Janet, et al.
Published: (2017)

Extra-cellular matrix proteins induce matrix metalloproteinase-1 (MMP-1) activity and increase airway smooth muscle contraction in asthma
by: Rogers, Natasha K., et al.
Published: (2014)

Isolation and screening of an extracellular organic solvent-tolerant protease producer
by: Geok, Lee Poh, et al.
Published: (2003)

Are reduced acidification rates a feasible, achievable option for future agricultural systems?
by: Fisher, James, et al.
Published: (2008)

A case of lymphangioleiomyomatosis with multiple angiomyolipomas in the kidneys: a case report
by: How, Soon Hin, et al.
Published: (2006)

Plackett-Burman design for the optimization of a novel extracellular marine protease production
by: Dehimi, Maya, et al.
Published: (2020)

The production of extracellular protease using bacillus subtilis : effect of temperature and agitation speed
by: Mohd Fadli, Abdullah
Published: (2006)

CRISPR-Cas9-mediated genome editing of the extracellular matrix gene TNC in human fibroblasts
by: Brunetti, Giulio
Published: (2017)

Crystallographic, DFT and docking (cathepsin B) studies on an organotellurium(IV) compound
by: Caracelli, Ignez, et al.
Published: (2016)

Aluminium sulphate (alum) recovery by acidification on the water treatment sludge
by: Mohd Firdaus, Che Dolah
Published: (2006)

Cloning, sequencing and extracellular expression of the alkaline protease gene from Bacillus stearothermophilus F1
by: Fu, Zhibiao
Published: (2001)

Pain prediction by serum biomarkers of bone turnover in people with knee osteoarthritis: an observational study of TRAcP5b and cathepsin K in OA
by: Nwosu, Lilian Ngozi, et al.
Published: (2017)

Maggots and wound healing: the effects of Lucilia sericata larval secretions upon interactions between human dermal fibroblasts and extracellular matrix proteins
by: Horobin, Adele Jayne
Published: (2005)

ECM crosslinking enhances fibroblast growth and protects against matrix proteolysis in lung fibrosis
by: Philp, Christopher J., et al.
Published: (2017)

Molecular identification of cathepsin L gene from Chrysomya megacephala and Lucilia cuprina
by: Kayan, Imba
Published: (2014)

A lifetime’s adventure in extracellular K+ regulation: the Scottish connection
by: Brown, Angus M.
Published: (2017)

Development of bovine cartilage extracellular matrix as a potential scaffold for chondrogenic induction of human dermal fibroblasts / Ali Moradi
by: Moradi, Ali
Published: (2015)

Optimization of soil acidification in landfill using wood ash / Fatihah Abdullah
by: Abdullah, Fatihah
Published: (2016)

Pseudomonas aeruginosa strain K and production of protease therefrom
by: Raja Abdul Rahman, Raja Noor Zaliha, et al.
Published: (2003)

Molecular characterisation and expression analysis of cathepsin D from the Asian seabass lates calcarifer
by: Shariza Azizan,, et al.
Published: (2014)

Design and scale up of vacuum distillation process for the acidification of crude palm oil
by: Abd. Aziz, Mustafa Kamal, et al.
Published: (1993)

An organic solvent-tolerant protease from Pseudomonas aeruginosa strain K: nutritional factors affecting protease production
by: Raja Abdul Rahman, Raja Noor Zaliha, et al.
Published: (2005)

Cellular acidification as a new approach to cancer treatment and to the understanding and therapeutics of neurodegenerative diseases
by: Harguindey, Salvador, et al.
Published: (2017)

Investigation of Tasik Perdana and Tasik Titiwangsa acidification process / Muhammad Hariz Abdul Rahman
by: Abdul Rahman, Muhammad Hariz
Published: (2010)

Investigation of surface water acidification at Semenyih dam water resource area / Annur Aiman Baharudin
by: Baharudin, Annur Aiman
Published: (2008)

Use of the Critical Acidification Model to Estimate Critical Localized Corrosion Potentials of Duplex Stainless Steels
by: Iannuzzi, Mariano, et al.
Published: (2016)

Preliminary Study on the Production of Extracellular Protease from a Newly Isolated Bacillus sp. (No.1) and the Physical Factors Affecting Its Production
by: Abdul Razak, Che Nyonya, et al.
Published: (1997)

Characterization of an Organic Solvent-Tolerant Protease from Pseudomonas Aeruginosa Strain K
by: Lee, Poh Geok
Published: (2003)

An analysis of the likely success of policy actions under uncertainty: recovery from acidification across Great Britain
by: Whyatt, J. Duncan, et al.
Published: (2017)

A quantitative genetic approach to assess the evolutionary potential of a coastal marine fish to ocean acidification
by: Malvezzi, A.J., et al.
Published: (2015)

Modelling the effect of fermentation temperature and time on starter culture growth, acidification and firmness in made-in-transit yoghurt
by: Mahmud @ Ab Rashid, Nor-Khaizura, et al.
Published: (2019)

Effect of Storage on the Changes in Cathepsin D Activity, Nucleotide Contents, Peptide Profiles and Muscle Ultrastructure of Aristichthys Nobilis, R
by: Bakar, Jamilah
Published: (1993)