Pain in knee osteoarthritis is associated with variation in the neurokinin 1/substance P receptor (TACR 1) gene

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Pain in knee osteoarthritis is associated with variation in the neurokinin 1/substance P receptor (TACR 1) gene

Background: Substance P (SP) is a pain- and inflammation-related neuropeptide which preferentially binds to the neurokinin receptor 1 (NK1). SP and NK1 receptors have been implicated in joint pain, inflammation and damage in animal models and human studies of osteoarthritis (OA). The aim of this stu...

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Bibliographic Details
Main Authors:	Warner, Sophie C., Walsh, David A., Laslett, L.L., Maciewicz, R.A., Soni, A., Hart, D.J., Zhang, Weiya, Muir, K.R., Dennison, E.M., Leaverton, P., Rampersaud, E., Cooper, C., Spector, T.D., Cicuttini, F.M., Arden, N.K., Jones, G., Doherty, M., Valdes, Ana M.
Format:	Article
Published:	Wiley 2017
Online Access:	https://eprints.nottingham.ac.uk/42828/

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