Rational drug repurposing using sscMap analysis in a HOX-TALE model of leukemia

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Rational drug repurposing using sscMap analysis in a HOX-TALE model of leukemia

Drug discovery and development are often hampered by lack of target identification and clinical tractability. Repurposing of approved drugs to life-threatening diseases such as leukemia is emerging as a promising alternative approach. Connectivity mapping systems link approved drugs with disease-rel...

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Bibliographic Details
Main Authors:	Kettyle, Laura M.J., Liberante, Fabio G., Thompson, Alexander
Format:	Article
Published:	Springer Verlag 2014
Subjects:	HOXA9 Meis1 Data mining Gene expression profiles Connectivity mapping (sscMap) Leukemia Entinostat Preclinical model
Online Access:	https://eprints.nottingham.ac.uk/42819/

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