Viscosity development during aqueous dispersion and dissolution: a comparison of PGX® with other dietary supplements and individual polysaccharides

Viscosity development with time was studied during the aqueous dissolution of the novel polysaccharide complex PGX®, a finer particle size version used in meal replacement PGXf, and a blend of the three polysaccharides 3PB used in their manufacture. Results were compared with those of single polysac...

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Main Authors: Smith, Ian H., Lawson, Christopher J., Harding, Stephen E., Gahler, Roland J., Lyon, Michael R., Wood, Simon
Format: Article
Published: Elsevier 2014
Subjects:
Online Access:https://eprints.nottingham.ac.uk/42751/
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author Smith, Ian H.
Lawson, Christopher J.
Harding, Stephen E.
Gahler, Roland J.
Lyon, Michael R.
Wood, Simon
author_facet Smith, Ian H.
Lawson, Christopher J.
Harding, Stephen E.
Gahler, Roland J.
Lyon, Michael R.
Wood, Simon
author_sort Smith, Ian H.
building Nottingham Research Data Repository
collection Online Access
description Viscosity development with time was studied during the aqueous dissolution of the novel polysaccharide complex PGX®, a finer particle size version used in meal replacement PGXf, and a blend of the three polysaccharides 3PB used in their manufacture. Results were compared with those of single polysaccharides and other commercially available soluble-fibre supplements. Measurements were made at 25.0 C in a rheometer vane and cup system at ~1000 s-1. Samples suspended in low MW PEG were discharged from a syringe into water under shear in the measuring system. Final mixtures contained 0.5% w/w sample and 2% w/w PEG. Most samples reaching high final equilibrium/ultimate viscosities (12e138 mPa s), appeared to dissolve completely within 1 h but four samples required 1.5 to >14 h. PGX®, PGXf and 3PB gave the highest ultimate viscosities within timescales relevant to stomach emptying. Viscosityetime data were reasonably reproducible except those for xanthan gum. Distinct steps in viscosity development curves for 3PB and Biomed Type 2 were attributed to different dissolution rates of their component polysaccharides. For samples reaching final viscosities < 12 mPa s, dietary fibre products often left residues of insoluble material whilst single polysaccharides appeared to dissolve completely. Attempts at curve fitting the dissolution profiles to single-exponential or logarithmic models failed. Better representations were obtained using a two-component exponential model due to Kravtchenko, Renoir, Parker, and Brigand (1999) or a four-component extension of this model. Dissolution rates were also compared using time to reach 50 and 80% of the ultimate viscosity at full dissolution.
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spelling nottingham-427512020-05-04T16:50:18Z https://eprints.nottingham.ac.uk/42751/ Viscosity development during aqueous dispersion and dissolution: a comparison of PGX® with other dietary supplements and individual polysaccharides Smith, Ian H. Lawson, Christopher J. Harding, Stephen E. Gahler, Roland J. Lyon, Michael R. Wood, Simon Viscosity development with time was studied during the aqueous dissolution of the novel polysaccharide complex PGX®, a finer particle size version used in meal replacement PGXf, and a blend of the three polysaccharides 3PB used in their manufacture. Results were compared with those of single polysaccharides and other commercially available soluble-fibre supplements. Measurements were made at 25.0 C in a rheometer vane and cup system at ~1000 s-1. Samples suspended in low MW PEG were discharged from a syringe into water under shear in the measuring system. Final mixtures contained 0.5% w/w sample and 2% w/w PEG. Most samples reaching high final equilibrium/ultimate viscosities (12e138 mPa s), appeared to dissolve completely within 1 h but four samples required 1.5 to >14 h. PGX®, PGXf and 3PB gave the highest ultimate viscosities within timescales relevant to stomach emptying. Viscosityetime data were reasonably reproducible except those for xanthan gum. Distinct steps in viscosity development curves for 3PB and Biomed Type 2 were attributed to different dissolution rates of their component polysaccharides. For samples reaching final viscosities < 12 mPa s, dietary fibre products often left residues of insoluble material whilst single polysaccharides appeared to dissolve completely. Attempts at curve fitting the dissolution profiles to single-exponential or logarithmic models failed. Better representations were obtained using a two-component exponential model due to Kravtchenko, Renoir, Parker, and Brigand (1999) or a four-component extension of this model. Dissolution rates were also compared using time to reach 50 and 80% of the ultimate viscosity at full dissolution. Elsevier 2014-07-31 Article PeerReviewed Smith, Ian H., Lawson, Christopher J., Harding, Stephen E., Gahler, Roland J., Lyon, Michael R. and Wood, Simon (2014) Viscosity development during aqueous dispersion and dissolution: a comparison of PGX® with other dietary supplements and individual polysaccharides. Food Hydrocolloids, 38 . pp. 152-162. ISSN 0268-005X Polysaccharide dissolution ; Dietary supplement dissolution ; Viscosity development ; Vane and cup viscometry ; PGX® ; PolyGlycopleX® http://www.sciencedirect.com/science/article/pii/S0268005X13003883 doi:10.1016/j.foodhyd.2013.12.004 doi:10.1016/j.foodhyd.2013.12.004
spellingShingle Polysaccharide dissolution ; Dietary supplement dissolution ; Viscosity development ; Vane and cup viscometry ; PGX® ; PolyGlycopleX®
Smith, Ian H.
Lawson, Christopher J.
Harding, Stephen E.
Gahler, Roland J.
Lyon, Michael R.
Wood, Simon
Viscosity development during aqueous dispersion and dissolution: a comparison of PGX® with other dietary supplements and individual polysaccharides
title Viscosity development during aqueous dispersion and dissolution: a comparison of PGX® with other dietary supplements and individual polysaccharides
title_full Viscosity development during aqueous dispersion and dissolution: a comparison of PGX® with other dietary supplements and individual polysaccharides
title_fullStr Viscosity development during aqueous dispersion and dissolution: a comparison of PGX® with other dietary supplements and individual polysaccharides
title_full_unstemmed Viscosity development during aqueous dispersion and dissolution: a comparison of PGX® with other dietary supplements and individual polysaccharides
title_short Viscosity development during aqueous dispersion and dissolution: a comparison of PGX® with other dietary supplements and individual polysaccharides
title_sort viscosity development during aqueous dispersion and dissolution: a comparison of pgx® with other dietary supplements and individual polysaccharides
topic Polysaccharide dissolution ; Dietary supplement dissolution ; Viscosity development ; Vane and cup viscometry ; PGX® ; PolyGlycopleX®
url https://eprints.nottingham.ac.uk/42751/
https://eprints.nottingham.ac.uk/42751/
https://eprints.nottingham.ac.uk/42751/