Ventral striatum connectivity during reward anticipation in adolescent smokers
Substance misusers, including adolescent smokers, often have reduced reward system activity during processing of non-drug rewards. Using a psychophysiological interaction approach, we examined functional connectivity with the ventral striatum during reward anticipation in a large (N = 206) sample of...
| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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| Format: | Article |
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Taylor & Francis
2016
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| Online Access: | https://eprints.nottingham.ac.uk/42634/ |
| _version_ | 1848796532821721088 |
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| author | Jollans, Lee Zhipeng, Cao Icke, Ilknur Greene, Ciara Kelly, Clare Banaschewski, Tobias Bokde, Arun L. W. Bromberg, Uli Büchel, Christian Cattrell, Anna Conrod, Patricia J. Desrivières, Sylvane Flor, Herta Frouin, Vincent Gallinat, Jürgen Garavan, Hugh Gowland, Penny Heinz, Andreas Ittermann, Bernd Martinot, Jean-Luc Artiges, Eric Nees, Frauke Papadopoulos Orfanos, Dimitri Paus, Tomáš Smolka, Michael N. Walter, Henrik Schumann, Gunter Whelan, Robert |
| author_facet | Jollans, Lee Zhipeng, Cao Icke, Ilknur Greene, Ciara Kelly, Clare Banaschewski, Tobias Bokde, Arun L. W. Bromberg, Uli Büchel, Christian Cattrell, Anna Conrod, Patricia J. Desrivières, Sylvane Flor, Herta Frouin, Vincent Gallinat, Jürgen Garavan, Hugh Gowland, Penny Heinz, Andreas Ittermann, Bernd Martinot, Jean-Luc Artiges, Eric Nees, Frauke Papadopoulos Orfanos, Dimitri Paus, Tomáš Smolka, Michael N. Walter, Henrik Schumann, Gunter Whelan, Robert |
| author_sort | Jollans, Lee |
| building | Nottingham Research Data Repository |
| collection | Online Access |
| description | Substance misusers, including adolescent smokers, often have reduced reward system activity during processing of non-drug rewards. Using a psychophysiological interaction approach, we examined functional connectivity with the ventral striatum during reward anticipation in a large (N = 206) sample of adolescent smokers. Increased smoking frequency was associated with (1) increased connectivity with regions involved in saliency and valuation, including the orbitofrontal cortex and (2) reduced connectivity between the ventral striatum and regions associated with inhibition and risk aversion, including the right inferior frontal gyrus. These results demonstrate that functional connectivity during reward processing is relevant to adolescent addiction. |
| first_indexed | 2025-11-14T19:49:29Z |
| format | Article |
| id | nottingham-42634 |
| institution | University of Nottingham Malaysia Campus |
| institution_category | Local University |
| last_indexed | 2025-11-14T19:49:29Z |
| publishDate | 2016 |
| publisher | Taylor & Francis |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | nottingham-426342020-05-04T17:46:51Z https://eprints.nottingham.ac.uk/42634/ Ventral striatum connectivity during reward anticipation in adolescent smokers Jollans, Lee Zhipeng, Cao Icke, Ilknur Greene, Ciara Kelly, Clare Banaschewski, Tobias Bokde, Arun L. W. Bromberg, Uli Büchel, Christian Cattrell, Anna Conrod, Patricia J. Desrivières, Sylvane Flor, Herta Frouin, Vincent Gallinat, Jürgen Garavan, Hugh Gowland, Penny Heinz, Andreas Ittermann, Bernd Martinot, Jean-Luc Artiges, Eric Nees, Frauke Papadopoulos Orfanos, Dimitri Paus, Tomáš Smolka, Michael N. Walter, Henrik Schumann, Gunter Whelan, Robert Substance misusers, including adolescent smokers, often have reduced reward system activity during processing of non-drug rewards. Using a psychophysiological interaction approach, we examined functional connectivity with the ventral striatum during reward anticipation in a large (N = 206) sample of adolescent smokers. Increased smoking frequency was associated with (1) increased connectivity with regions involved in saliency and valuation, including the orbitofrontal cortex and (2) reduced connectivity between the ventral striatum and regions associated with inhibition and risk aversion, including the right inferior frontal gyrus. These results demonstrate that functional connectivity during reward processing is relevant to adolescent addiction. Taylor & Francis 2016-04-13 Article PeerReviewed Jollans, Lee, Zhipeng, Cao, Icke, Ilknur, Greene, Ciara, Kelly, Clare, Banaschewski, Tobias, Bokde, Arun L. W., Bromberg, Uli, Büchel, Christian, Cattrell, Anna, Conrod, Patricia J., Desrivières, Sylvane, Flor, Herta, Frouin, Vincent, Gallinat, Jürgen, Garavan, Hugh, Gowland, Penny, Heinz, Andreas, Ittermann, Bernd, Martinot, Jean-Luc, Artiges, Eric, Nees, Frauke, Papadopoulos Orfanos, Dimitri, Paus, Tomáš, Smolka, Michael N., Walter, Henrik, Schumann, Gunter and Whelan, Robert (2016) Ventral striatum connectivity during reward anticipation in adolescent smokers. Developmental Neuropsychology, 41 (1-2). pp. 6-21. ISSN 1532-6942 http://www.tandfonline.com/doi/full/10.1080/87565641.2016.1164172 doi:10.1080/87565641.2016.1164172 doi:10.1080/87565641.2016.1164172 |
| spellingShingle | Jollans, Lee Zhipeng, Cao Icke, Ilknur Greene, Ciara Kelly, Clare Banaschewski, Tobias Bokde, Arun L. W. Bromberg, Uli Büchel, Christian Cattrell, Anna Conrod, Patricia J. Desrivières, Sylvane Flor, Herta Frouin, Vincent Gallinat, Jürgen Garavan, Hugh Gowland, Penny Heinz, Andreas Ittermann, Bernd Martinot, Jean-Luc Artiges, Eric Nees, Frauke Papadopoulos Orfanos, Dimitri Paus, Tomáš Smolka, Michael N. Walter, Henrik Schumann, Gunter Whelan, Robert Ventral striatum connectivity during reward anticipation in adolescent smokers |
| title | Ventral striatum connectivity during reward anticipation in adolescent smokers |
| title_full | Ventral striatum connectivity during reward anticipation in adolescent smokers |
| title_fullStr | Ventral striatum connectivity during reward anticipation in adolescent smokers |
| title_full_unstemmed | Ventral striatum connectivity during reward anticipation in adolescent smokers |
| title_short | Ventral striatum connectivity during reward anticipation in adolescent smokers |
| title_sort | ventral striatum connectivity during reward anticipation in adolescent smokers |
| url | https://eprints.nottingham.ac.uk/42634/ https://eprints.nottingham.ac.uk/42634/ https://eprints.nottingham.ac.uk/42634/ |