Effect of hyperacute administration (within 6 hours) of transdermal glyceryl trinitrate, a nitric oxide donor, on outcome after stroke
Background and Purpose — Nitric oxide donors are candidate treatments for acute stroke, potentially through hemodynamic, reperfusion, and neuroprotectant effects, especially if given early. Although the large Efficacy of Nitric Oxide in Stroke (ENOS) trial of transdermal glyceryl trinitrate (GTN) wa...
| Main Authors: | Woodhouse, Lisa J., Scutt, Polly, Krishnan, Kailash, Berge, Eivind, Gommans, John, Ntaios, George, Wardlaw, Joanna M., Sprigg, Nikola, Bath, Philip M.W. |
|---|---|
| Format: | Article |
| Published: |
American Heart Association
2015
|
| Subjects: | |
| Online Access: | https://eprints.nottingham.ac.uk/42630/ |
Similar Items
Ambulance-delivered transdermal glyceryl trinitrate versus sham for ultra-acute stroke: rationale, design and protocol for the Rapid Intervention with Glyceryl trinitrate in Hypertensive stroke Trial-2 (RIGHT-2) trial (ISRCTN26986053)
by: Appleton, Jason P., et al.
Published: (2017)
by: Appleton, Jason P., et al.
Published: (2017)
Statistical analysis plan for the ‘Rapid Intervention with Glyceryl trinitrate in Hypertensive stroke Trial-2 (RIGHT-2)’
by: Scutt, Polly, et al.
Published: (2018)
by: Scutt, Polly, et al.
Published: (2018)
Glyceryl trinitrate for acute intracerebral hemorrhage: results from the efficacy of nitric oxide in stroke (ENOS) trial, a subgroup analysis
by: Krishnan, Kailash, et al.
Published: (2015)
by: Krishnan, Kailash, et al.
Published: (2015)
Therapeutic potential of transdermal glyceryl trinitrate in the management of acute stroke
by: Appleton, Jason P., et al.
Published: (2016)
by: Appleton, Jason P., et al.
Published: (2016)
Rapid intervention with glyceryl trinitrate in hypertensive stroke trial-2(right-2): safety and efficacy of transdermal glyceryl trinitrate, a nitric oxide donor
by: Dixon, M., et al.
Published: (2018)
by: Dixon, M., et al.
Published: (2018)
The role of glyceryl trinitrate, a nitric oxide donor, in acute stroke
by: Appleton, Jason Philip
Published: (2019)
by: Appleton, Jason Philip
Published: (2019)
Statistical analysis plan for the ‘Tranexamic acid for hyperacute primary IntraCerebral Haemorrhage’ (TICH-2) trial
by: Flaherty, Katie, et al.
Published: (2017)
by: Flaherty, Katie, et al.
Published: (2017)
Rapid Intervention with Glyceryl trinitrate in Hypertensive stroke Trial-2 (RIGHT-2): safety and efficacy of transdermal glyceryl trinitrate, a nitric oxide donor, and of the feasibility of a multicentre ambulance-based stroke trial
by: Dixon, Mark, et al.
Published: (2018)
by: Dixon, Mark, et al.
Published: (2018)
The effect of transdermal glyceryl trinitrate in acute stroke patients with carotid stenosis: data from the Efficacy of Nitric Oxide in Stroke trial
by: Appleton, J.P., et al.
Published: (2018)
by: Appleton, J.P., et al.
Published: (2018)
Route of feeding as a proxy for dysphagia after stroke and the effect of transdermal glyceryl trinitrate: data from the efficacy of nitric oxide in stroke randomised controlled trial
by: Woodhouse, Lisa J., et al.
Published: (2017)
by: Woodhouse, Lisa J., et al.
Published: (2017)
Tranexamic acid for hyperacute primary IntraCerebral Haemorrhage (TICH-2): an international randomised, placebo-controlled, phase 3 superiority trial
by: Sprigg, Nikola, et al.
Published: (2018)
by: Sprigg, Nikola, et al.
Published: (2018)
Effect of treatment delay, stroke type, and thrombolysis on the effect of glyceryl trinitrate, a nitric oxide donor, on outcome after acute stroke: a systematic review and meta-analysis of individual patient from randomised trials
by: Bath, Philip M.W., et al.
Published: (2016)
by: Bath, Philip M.W., et al.
Published: (2016)
Consent procedures and relationship with outcome in the Rapid Intervention with Glyceryl trinitrate in Hypertensive stroke Trial-2 (RIGHT-2)
by: Scutt, Polly, et al.
Published: (2018)
by: Scutt, Polly, et al.
Published: (2018)
Impact of ultra/hyper-acute administration of glyceryl trinitrate on secondary outcome after acute stroke: a meta-analysis of individual patient data from randomised trials
by: Bath, Philip M., et al.
Published: (2018)
by: Bath, Philip M., et al.
Published: (2018)
Relationship between race and outcome in Asian, Black and Caucasian patients with spontaneous intracerebral haemorrhage: data from the Virtual International Stroke Trials Archive (VISTA) and Efficacy of Nitric Oxide in Stroke trial (ENOS)
by: Krishnan, Kailash, et al.
Published: (2018)
by: Krishnan, Kailash, et al.
Published: (2018)
The effect of transdermal glyceryl trinitrate on imaging characteristics in acute ischaemic stroke: data from the Efficacy of Nitric Oxide in Stroke trial
by: Appleton, Jason P.
Published: (2018)
by: Appleton, Jason P.
Published: (2018)
Interim analysis of ambulance logistics and timings in patients recruited into the Rapid intervention with Glyceryl trinitrate in Hypertensive stroke Trial-2 (RIGHT-2)
by: Dixon, Mark, et al.
Published: (2018)
by: Dixon, Mark, et al.
Published: (2018)
Outcomes after acute intracerebral haemorrhage
by: Krishnan, Kailash
Published: (2017)
by: Krishnan, Kailash
Published: (2017)
Blood pressure in acute stroke: to treat or not to treat - that is still the question
by: Bath, Philip M.W., et al.
Published: (2018)
by: Bath, Philip M.W., et al.
Published: (2018)
Management of acute intracerebral haemorrhage – an update
by: Law, Zhe Kang, et al.
Published: (2017)
by: Law, Zhe Kang, et al.
Published: (2017)
In vivo survivality and optimization of parameters for biomass production of GDHA derivative of pasteurella multocida B:2
by: Oslan, Siti Nur Hazwani
Published: (2013)
by: Oslan, Siti Nur Hazwani
Published: (2013)
Field trials of live gdhA derivative pasteurella multicida B:2 vaccine against haemorrhagic septicaemia in buffaloes
by: Othman, Rafidah
Published: (2013)
by: Othman, Rafidah
Published: (2013)
The changing function of nitric oxide in the ventral cochlear nucleus during tinnitus
by: Hockley, Adam
Published: (2019)
by: Hockley, Adam
Published: (2019)
Prevention of haematoma progression by tranexamic acid in intracerebral haemorrhage patients with and without spot sign on admission scan: a statistical analysis plan of a pre-specified sub-study of the TICH-2 trial
by: Ovesen, Christian, et al.
Published: (2018)
by: Ovesen, Christian, et al.
Published: (2018)
A systematic review of nitric oxide donors and L-arginine in experimental stroke: effects on infarct size and cerebral blood flow
by: Willmot, Mark, et al.
Published: (2005)
by: Willmot, Mark, et al.
Published: (2005)
Development and validation of segmental length equations to estimate height among cerebral palsy children in southern and central regions of Peninsular Malaysia
by: Mokhy, Mahnon Suria
Published: (2021)
by: Mokhy, Mahnon Suria
Published: (2021)
Pharmacological treatment and prevention of cerebral small vessel disease: a review of potential interventions
by: Bath, Philip M.W., et al.
Published: (2015)
by: Bath, Philip M.W., et al.
Published: (2015)
Removal of Lead (II) By Nitric Acid-Modified Activated Carbon
by: Loo, Li Yin
Published: (2006)
by: Loo, Li Yin
Published: (2006)
Evaluation of 25 midline cerebral structures of infants by three dimensional ultrasound at a public hospital in Malaysia
by: Norhafidzah, Mohamed Sharif
Published: (2017)
by: Norhafidzah, Mohamed Sharif
Published: (2017)
Functional analysis of nitric oxide in Musa sp. cv. Berangan during interaction with Fusarium oxysporum f. sp. cubense Tropical Race 4
by: Mohd Nasir, Nurul Najihah
Published: (2018)
by: Mohd Nasir, Nurul Najihah
Published: (2018)
The epidemiology of hereditary haemorrhagic telangiectasia and pulmonary arteriovenous malformations
by: Donaldson, James W.
Published: (2016)
by: Donaldson, James W.
Published: (2016)
The REstart or STop Antithrombotics Randomised Trial (RESTART) after stroke due to intracerebral haemorrhage: study protocol for a randomised controlled trial
by: Al-Shahi Salman, Rustam, et al.
Published: (2018)
by: Al-Shahi Salman, Rustam, et al.
Published: (2018)
MRI in hyperacute stroke: early experience
by: Kamis, Mohd Fandi Al-Khafiz, et al.
Published: (2023)
by: Kamis, Mohd Fandi Al-Khafiz, et al.
Published: (2023)
Identification of disrupted molecular networks involved in brain maturation and function in the TS1CJE mouse model of down syndrome
by: Tan, Kai Leng
Published: (2016)
by: Tan, Kai Leng
Published: (2016)
Internal mammary artery smooth muscle cells resist migration and possess high antioxidant capacity
by: Mahadevan, Vaikom, et al.
Published: (2006)
by: Mahadevan, Vaikom, et al.
Published: (2006)
Does tranexamic acid lead to changes in MRI-measures of brain tissue health in patients with spontaneous intracerebral haemorrhage? An MRI sub-study nested within the double-blind randomised controlled TICH-2 trial
by: Dineen, Robert A., et al.
Published: (2018)
by: Dineen, Robert A., et al.
Published: (2018)
Treatment of intracerebral haemorrhage with tranexamic acid: a review of current evidence and ongoing trials
by: Law, Zhe Kang, et al.
Published: (2016)
by: Law, Zhe Kang, et al.
Published: (2016)
Hypercholesterolaemia and vascular dementia
by: Appleton, Jason P., et al.
Published: (2017)
by: Appleton, Jason P., et al.
Published: (2017)
Antiplatelet therapy following ischaemic stroke: continue or change pre-existing therapy?
by: Mazlan-Kepli, Wardati, et al.
Published: (2017)
by: Mazlan-Kepli, Wardati, et al.
Published: (2017)
Continuing or temporarily stopping prestroke antihypertensive medication in acute stroke: an individual patient data meta-analysis
by: Woodhouse, Lisa J., et al.
Published: (2017)
by: Woodhouse, Lisa J., et al.
Published: (2017)
Similar Items
-
Ambulance-delivered transdermal glyceryl trinitrate versus sham for ultra-acute stroke: rationale, design and protocol for the Rapid Intervention with Glyceryl trinitrate in Hypertensive stroke Trial-2 (RIGHT-2) trial (ISRCTN26986053)
by: Appleton, Jason P., et al.
Published: (2017) -
Statistical analysis plan for the ‘Rapid Intervention with Glyceryl trinitrate in Hypertensive stroke Trial-2 (RIGHT-2)’
by: Scutt, Polly, et al.
Published: (2018) -
Glyceryl trinitrate for acute intracerebral hemorrhage: results from the efficacy of nitric oxide in stroke (ENOS) trial, a subgroup analysis
by: Krishnan, Kailash, et al.
Published: (2015) -
Therapeutic potential of transdermal glyceryl trinitrate in the management of acute stroke
by: Appleton, Jason P., et al.
Published: (2016) -
Rapid intervention with glyceryl trinitrate in hypertensive stroke trial-2(right-2): safety and efficacy of transdermal glyceryl trinitrate, a nitric oxide donor
by: Dixon, M., et al.
Published: (2018)