Imaging Pain Relief in Osteoarthritis (IPRO): protocol of a double-blind randomised controlled mechanistic study assessing pain relief and prediction of duloxetine treatment outcome

Imaging Pain Relief in Osteoarthritis (IPRO): protocol of a double-blind randomised controlled mechanistic study assessing pain relief and prediction of duloxetine treatment outcome

Introduction: Osteoarthritis (OA) pain is a major cause of long-term disability and chronic pain in the adult population. One in five patients does not receive satisfactory pain relief, which reflects the complexity of chronic pain and the current lack of understanding of mechanisms of chronic pain....

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Bibliographic Details
Main Authors: Reckziegel, Diane, Bailey, Helen, Cottam, William J., Tench, Christopher R., Mahajan, Ravi P., Walsh, David A., Knaggs, Roger, Auer, Dorothee P.
Format: Article
Published: BMJ Publishing Group 2017
Subjects:
Osteoarthritis pain
magnetic resonance imaging
fMRI
analgesia
duloxetine
antidepressant
Online Access:https://eprints.nottingham.ac.uk/42561/

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