Longitudinal change in collagen degradation biomarkers in idiopathic pulmonary fibrosis: an analysis from the prospective, multicentre PROFILE study

Longitudinal change in collagen degradation biomarkers in idiopathic pulmonary fibrosis: an analysis from the prospective, multicentre PROFILE study

BACKGROUND: Idiopathic pulmonary fibrosis, a progressive and inevitably fatal disorder, has a highly variable clinical course. Biomarkers that reflect disease activity are urgently needed to inform patient management and for use as biomarkers of therapeutic response (theragnostic biomarkers) in clin...

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Main Authors: Jenkins, R. Gisli, Simpson, Juliet K., Saini, Gauri, Bentley, Jane H., Russell, Anne-Marie, Braybrooke, Rebecca, Molyneux, Philip L., McKeever, Tricia M., Wells, Athol U., Flynn, Aiden, Hubbard, Richard B., Leeming, Diana J., Marshall, Richard P., Karsdal, Morten A., Lukey, Pauline T., Maher, Toby M.
Format: Article
Published: Elsevier 2015
Subjects:
Aged; Biomarkers/blood; Cohort Studies; Collagen/*blood; Enzyme-Linked Immunosorbent Assay; Female Follow-Up Studies Humans Idiopathic Pulmonary Fibrosis/*blood Longitudinal Studies Male Matrix Metalloproteinases/*blood Prospective Studies
Online Access:https://eprints.nottingham.ac.uk/42455/

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